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@prefix citation: <http://purl.uniprot.org/citations/> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix disease: <http://purl.uniprot.org/diseases/> .
@prefix ECO: <http://purl.obolibrary.org/obo/ECO_> .
@prefix enzyme: <http://purl.uniprot.org/enzyme/> .
@prefix faldo: <http://biohackathon.org/resource/faldo#> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix go: <http://purl.obolibrary.org/obo/GO_> .
@prefix isoform: <http://purl.uniprot.org/isoforms/> .
@prefix keyword: <http://purl.uniprot.org/keywords/> .
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@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix position: <http://purl.uniprot.org/position/> .
@prefix pubmed: <http://purl.uniprot.org/pubmed/> .
@prefix range: <http://purl.uniprot.org/range/> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix taxon: <http://purl.uniprot.org/taxonomy/> .
@prefix tissue: <http://purl.uniprot.org/tissues/> .
@prefix up: <http://purl.uniprot.org/core/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
<D6RHD2> rdf:type up:Protein ;
  up:reviewed false ;
  up:created "2010-07-13"^^xsd:date ;
  up:modified "2024-05-29"^^xsd:date ;
  up:version 85 ;
  up:mnemonic "D6RHD2_HUMAN" ;
  up:citation citation:15815621 ,
    citation:22223895 ,
    citation:SIPD6E2BA06193ECDE3 ;
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    <http://purl.uniprot.org/smr/D6RHD2> ,
    <http://purl.uniprot.org/massive/D6RHD2> ,
    <http://purl.uniprot.org/peptideatlas/D6RHD2> ,
    <http://purl.uniprot.org/proteomicsdb/14807> ,
    <http://purl.uniprot.org/antibodypedia/26880> ,
    <http://rdf.ebi.ac.uk/resource/ensembl.transcript/ENST00000507703.1> ,
    <http://purl.uniprot.org/ucsc/uc062zkw.1> ,
    <http://purl.uniprot.org/hgnc/11269> ,
    <http://purl.uniprot.org/veupathdb/HostDB:ENSG00000164056> ,
    <http://purl.uniprot.org/genetree/ENSGT00950000183055> ,
    <http://purl.uniprot.org/oma/YERESQP> ,
    <http://purl.uniprot.org/chitars/SPRY1> ,
    <http://purl.uniprot.org/bgee/ENSG00000164056> ,
    <http://purl.uniprot.org/expressionatlas/D6RHD2> ,
    <http://purl.uniprot.org/panther/PTHR12365:SF10> ,
    <http://purl.uniprot.org/panther/PTHR12365> ,
    <http://purl.uniprot.org/maxqb/D6RHD2> ;
  up:submittedName <D6RHD2#SIP24D031780D46D192> ;
  up:organism taxon:9606 ;
  up:encodedBy <D6RHD2#gene-MD543209D939A32CC6E55A8A35A44043C4D> ;
  up:annotation <D6RHD2#SIP18AE4094B1BA1F39> ,
    <D6RHD2#SIP7589FF02CDDC4502> ,
    <D6RHD2#SIPD610BEE97EF7678E> ,
    <D6RHD2#SIP7237A5F586CB99C3> ,
    <D6RHD2#SIPED2562962BC3B1EB> ;
  up:existence up:Evidence_at_Protein_Level_Existence ;
  up:classifiedWith keyword:1267 ,
    keyword:1185 ,
    go:0005829 ,
    go:0005794 ,
    go:0005654 ,
    go:0048513 ,
    go:0040037 ,
    go:0046580 ;
  up:sequence isoform:D6RHD2-1 ;
  up:attribution <D6RHD2#attribution-0E81843043DD29243798FB14E596DFF3> ,
    <D6RHD2#attribution-879CE807735CB618FA1DA5EB695C5782> ,
    <D6RHD2#attribution-0F3FDD096B9105C9DD73A250C39349DD> ,
    <D6RHD2#attribution-260F9275F08C92D1CF2D41553CB78263> ,
    <D6RHD2#attribution-51C14663A5EAD59431003793901E2BC8> ,
    <D6RHD2#attribution-54E2E2AB08CF4A3912901904EBC34839> ,
    <D6RHD2#attribution-8AC042D64E8866BA4EDF9552D7236A6D> ,
    <D6RHD2#attribution-C71E57C1A10EFC1FD9698F603841B38F> ,
    <D6RHD2#attribution-B6373A2BBA1F15CBD39BAB34E851AA52> ;
  up:proteome <http://purl.uniprot.org/proteomes/UP000005640#Chromosome%204> .
citation:15815621 rdf:type up:Journal_Citation ;
  up:title "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." ;
  up:author "Hillier L.W." ,
    "Graves T.A." ,
    "Fulton R.S." ,
    "Fulton L.A." ,
    "Pepin K.H." ,
    "Minx P." ,
    "Wagner-McPherson C." ,
    "Layman D." ,
    "Wylie K." ,
    "Sekhon M." ,
    "Becker M.C." ,
    "Fewell G.A." ,
    "Delehaunty K.D." ,
    "Miner T.L." ,
    "Nash W.E." ,
    "Kremitzki C." ,
    "Oddy L." ,
    "Du H." ,
    "Sun H." ,
    "Bradshaw-Cordum H." ,
    "Ali J." ,
    "Carter J." ,
    "Cordes M." ,
    "Harris A." ,
    "Isak A." ,
    "van Brunt A." ,
    "Nguyen C." ,
    "Du F." ,
    "Courtney L." ,
    "Kalicki J." ,
    "Ozersky P." ,
    "Abbott S." ,
    "Armstrong J." ,
    "Belter E.A." ,
    "Caruso L." ,
    "Cedroni M." ,
    "Cotton M." ,
    "Davidson T." ,
    "Desai A." ,
    "Elliott G." ,
    "Erb T." ,
    "Fronick C." ,
    "Gaige T." ,
    "Haakenson W." ,
    "Haglund K." ,
    "Holmes A." ,
    "Harkins R." ,
    "Kim K." ,
    "Kruchowski S.S." ,
    "Strong C.M." ,
    "Grewal N." ,
    "Goyea E." ,
    "Hou S." ,
    "Levy A." ,
    "Martinka S." ,
    "Mead K." ,
    "McLellan M.D." ,
    "Meyer R." ,
    "Randall-Maher J." ,
    "Tomlinson C." ,
    "Dauphin-Kohlberg S." ,
    "Kozlowicz-Reilly A." ,
    "Shah N." ,
    "Swearengen-Shahid S." ,
    "Snider J." ,
    "Strong J.T." ,
    "Thompson J." ,
    "Yoakum M." ,
    "Leonard S." ,
    "Pearman C." ,
    "Trani L." ,
    "Radionenko M." ,
    "Waligorski J.E." ,
    "Wang C." ,
    "Rock S.M." ,
    "Tin-Wollam A.-M." ,
    "Maupin R." ,
    "Latreille P." ,
    "Wendl M.C." ,
    "Yang S.-P." ,
    "Pohl C." ,
    "Wallis J.W." ,
    "Spieth J." ,
    "Bieri T.A." ,
    "Berkowicz N." ,
    "Nelson J.O." ,
    "Osborne J." ,
    "Ding L." ,
    "Meyer R.'" ,
    "Sabo A." ,
    "Shotland Y." ,
    "Sinha P." ,
    "Wohldmann P.E." ,
    "Cook L.L." ,
    "Hickenbotham M.T." ,
    "Eldred J." ,
    "Williams D." ,
    "Jones T.A." ,
    "She X." ,
    "Ciccarelli F.D." ,
    "Izaurralde E." ,
    "Taylor J." ,
    "Schmutz J." ,
    "Myers R.M." ,
    "Cox D.R." ,
    "Huang X." ,
    "McPherson J.D." ,
    "Mardis E.R." ,
    "Clifton S.W." ,
    "Warren W.C." ,
    "Chinwalla A.T." ,
    "Eddy S.R." ,
    "Marra M.A." ,
    "Ovcharenko I." ,
    "Furey T.S." ,
    "Miller W." ,
    "Eichler E.E." ,
    "Bork P." ,
    "Suyama M." ,
    "Torrents D." ,
    "Waterston R.H." ,
    "Wilson R.K." ;
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  up:date "2005"^^xsd:gYear ;
  up:name "Nature" ;
  up:volume "434" ;
  up:pages "724-731" .
<#_D6RHD2-citation-15815621> rdf:type rdf:Statement ;
  rdf:subject <D6RHD2> ;
  rdf:predicate up:citation ;
  rdf:object citation:15815621 ;
  rdf:type up:Citation_Statement ;
  up:scope "NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]" ;
  up:attribution <D6RHD2#attribution-51C14663A5EAD59431003793901E2BC8> ,
    <D6RHD2#attribution-54E2E2AB08CF4A3912901904EBC34839> .
citation:22223895 rdf:type up:Journal_Citation ;
  up:title "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features." ;
  up:author "Bienvenut W.V." ,
    "Sumpton D." ,
    "Martinez A." ,
    "Lilla S." ,
    "Espagne C." ,
    "Meinnel T." ,
    "Giglione C." ;
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  dcterms:identifier "doi:10.1074/mcp.M111.015131" ;
  up:date "2012"^^xsd:gYear ;
  up:name "Mol. Cell. Proteomics" ;
  up:volume "11" ;
  up:pages "M111.015131" .
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  rdf:subject <D6RHD2> ;
  rdf:predicate up:citation ;
  rdf:object citation:22223895 ;
  rdf:type up:Citation_Statement ;
  up:scope "IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]" ;
  up:attribution <D6RHD2#attribution-B6373A2BBA1F15CBD39BAB34E851AA52> .
citation:SIPD6E2BA06193ECDE3 rdf:type up:Submission_Citation ;
  up:group "Ensembl" ;
  up:date "2024-02"^^xsd:gYearMonth ;
  up:submittedTo "UniProtKB" .
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  up:database <http://purl.uniprot.org/database/SMR> .
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  up:database <http://purl.uniprot.org/database/MassIVE> .
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  up:database <http://purl.uniprot.org/database/PeptideAtlas> .
<http://purl.uniprot.org/proteomicsdb/14807> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/ProteomicsDB> .
<http://purl.uniprot.org/antibodypedia/26880> rdf:type up:Resource ;
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  rdfs:comment "286 antibodies from 31 providers" .
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  up:database <http://purl.uniprot.org/database/Ensembl> ;
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  up:transcribedFrom <http://rdf.ebi.ac.uk/resource/ensembl/ENSG00000164056.11> .
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  rdfs:comment "SPRY1" .
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  up:database <http://purl.uniprot.org/database/VEuPathDB> .
<http://purl.uniprot.org/genetree/ENSGT00950000183055> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/GeneTree> .
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  up:database <http://purl.uniprot.org/database/OMA> .
<http://purl.uniprot.org/chitars/SPRY1> rdf:type up:Resource ;
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  rdfs:comment "human" .
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  rdfs:comment "Expressed in pericardium and 190 other cell types or tissues" .
<http://purl.uniprot.org/expressionatlas/D6RHD2> rdf:type up:Resource ;
  up:database <http://purl.uniprot.org/database/ExpressionAtlas> ;
  rdfs:comment "baseline and differential" .
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  rdfs:comment "PROTEIN SPROUTY HOMOLOG 1" ;
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  up:database <http://purl.uniprot.org/database/PANTHER> ;
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<D6RHD2#SIP24D031780D46D192> rdf:type up:Structured_Name ;
  up:fullName "Sprouty RTK signaling antagonist 1" .
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  rdf:subject <D6RHD2#SIP24D031780D46D192> ;
  rdf:predicate up:fullName ;
  rdf:object "Sprouty RTK signaling antagonist 1" ;
  up:attribution <D6RHD2#attribution-51C14663A5EAD59431003793901E2BC8> .
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  rdf:subject <D6RHD2> ;
  rdf:predicate up:organism ;
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    <D6RHD2#attribution-54E2E2AB08CF4A3912901904EBC34839> .
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  skos:prefLabel "SPRY1" .
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  rdf:subject <D6RHD2#gene-MD543209D939A32CC6E55A8A35A44043C4D> ;
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  up:attribution <D6RHD2#attribution-51C14663A5EAD59431003793901E2BC8> .
<D6RHD2#SIP18AE4094B1BA1F39> rdf:type up:Subcellular_Location_Annotation ;
  up:locatedIn <D6RHD2#SIPBC0F00A87513E4E7> .
<D6RHD2#SIPBC0F00A87513E4E7> up:cellularComponent location:86 .
<#_AF8EBBCFF5EB2436_ECA11A063956BBD5_0AD494B8C8945D9B> rdf:type rdf:Statement ;
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  rdf:predicate up:cellularComponent ;
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  up:attribution <D6RHD2#attribution-0F3FDD096B9105C9DD73A250C39349DD> .
<D6RHD2#SIP7589FF02CDDC4502> rdf:type up:Region_Annotation ;
  rdfs:comment "Disordered" ;
  up:range range:19200025443971630tt54tt78 .
range:19200025443971630tt54tt78 rdf:type faldo:Region ;
  faldo:begin position:19200025443971630tt54 ;
  faldo:end position:19200025443971630tt78 .
position:19200025443971630tt54 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 54 ;
  faldo:reference isoform:D6RHD2-1 .
position:19200025443971630tt78 rdf:type faldo:Position ,
    faldo:ExactPosition ;
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  faldo:reference isoform:D6RHD2-1 .
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  rdfs:comment "Disordered" ;
  up:range range:19200025443971630tt100tt159 .
range:19200025443971630tt100tt159 rdf:type faldo:Region ;
  faldo:begin position:19200025443971630tt100 ;
  faldo:end position:19200025443971630tt159 .
position:19200025443971630tt100 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 100 ;
  faldo:reference isoform:D6RHD2-1 .
position:19200025443971630tt159 rdf:type faldo:Position ,
    faldo:ExactPosition ;
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  rdfs:comment "Polar residues" ;
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range:19200025443971630tt108tt137 rdf:type faldo:Region ;
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position:19200025443971630tt108 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 108 ;
  faldo:reference isoform:D6RHD2-1 .
position:19200025443971630tt137 rdf:type faldo:Position ,
    faldo:ExactPosition ;
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  faldo:reference isoform:D6RHD2-1 .
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range:19200025443971630tt209tt209 rdf:type faldo:Region ;
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position:19200025443971630tt209 rdf:type faldo:Position ,
    faldo:ExactPosition ;
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  rdf:object go:0005794 ;
  up:attribution <D6RHD2#attribution-0E81843043DD29243798FB14E596DFF3> .
<#_kb.D6RHD2_up.classifiedWith_obo.GO_0005654> rdf:type rdf:Statement ;
  rdf:subject <D6RHD2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0005654 ;
  up:attribution <D6RHD2#attribution-0E81843043DD29243798FB14E596DFF3> .
<#_kb.D6RHD2_up.classifiedWith_obo.GO_0048513> rdf:type rdf:Statement ;
  rdf:subject <D6RHD2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0048513 ;
  up:attribution <D6RHD2#attribution-879CE807735CB618FA1DA5EB695C5782> .
<#_kb.D6RHD2_up.classifiedWith_obo.GO_0040037> rdf:type rdf:Statement ;
  rdf:subject <D6RHD2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0040037 ;
  up:attribution <D6RHD2#attribution-879CE807735CB618FA1DA5EB695C5782> .
<#_kb.D6RHD2_up.classifiedWith_obo.GO_0046580> rdf:type rdf:Statement ;
  rdf:subject <D6RHD2> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0046580 ;
  up:attribution <D6RHD2#attribution-879CE807735CB618FA1DA5EB695C5782> .
isoform:D6RHD2-1 rdf:type up:Simple_Sequence ;
  up:modified "2010-07-13"^^xsd:date ;
  up:version 1 ;
  up:fragment "single" ;
  up:mass 22883 ;
  up:md5Checksum "a6db4c1e6667d67dc4ad0c24298b759a" ;
  rdf:value "MDPQNQHGSGSSLVVIQQPSLDSRQRLDYEREIQPTAILSLDQIKAIRGSNEYTEGPSVVKRPAPRTAPRQEKHERTHEIIPINVNNNYEHRHTSHLGHAVLPSNARGPILSRSTSTGSAASSGSNSSASSEQGLLGRSPPTRPVPGHRSERAIRTQPKQLIVDDLKGSLKEDLTQHKFICEQCGKCKCGECTAPRTLPSCLACNRQCL" .
<D6RHD2#attribution-0E81843043DD29243798FB14E596DFF3> dcterms:creator <http://purl.uniprot.org/goa-projects/HPA> ;
  up:manual true ;
  up:evidence ECO:0000314 .
<D6RHD2#attribution-879CE807735CB618FA1DA5EB695C5782> dcterms:creator <http://purl.uniprot.org/goa-projects/TreeGrafter> ;
  up:evidence ECO:0007669 .
<D6RHD2#attribution-0F3FDD096B9105C9DD73A250C39349DD> up:evidence ECO:0000256 ;
  up:source <http://purl.uniprot.org/arba/ARBA00004496> .
<D6RHD2#attribution-260F9275F08C92D1CF2D41553CB78263> up:evidence ECO:0000256 ;
  up:source <http://purl.uniprot.org/sam/MobiDB-lite> .
<D6RHD2#attribution-51C14663A5EAD59431003793901E2BC8> up:evidence ECO:0000313 ;
  up:source <http://rdf.ebi.ac.uk/resource/ensembl.protein/ENSP00000421036.1> .
<http://rdf.ebi.ac.uk/resource/ensembl.protein/ENSP00000421036.1> up:database <http://purl.uniprot.org/database/Ensembl> .
<D6RHD2#attribution-54E2E2AB08CF4A3912901904EBC34839> up:evidence ECO:0000313 ;
  up:source <http://purl.uniprot.org/proteomes/UP000005640> .
<D6RHD2#attribution-8AC042D64E8866BA4EDF9552D7236A6D> up:evidence ECO:0007829 ;
  up:source <http://purl.uniprot.org/epd/D6RHD2> .
<D6RHD2#attribution-C71E57C1A10EFC1FD9698F603841B38F> up:evidence ECO:0007829 ;
  up:source <http://purl.uniprot.org/maxqb/D6RHD2> .
<D6RHD2#attribution-B6373A2BBA1F15CBD39BAB34E851AA52> up:evidence ECO:0007829 ;
  up:source citation:22223895 .