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  up:reviewed false ;
  up:created "2011-07-27"^^xsd:date ;
  up:modified "2024-03-27"^^xsd:date ;
  up:version 59 ;
  up:mnemonic "F6XRK5_MONDO" ;
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    <F6XRK5#SIPACA5A473A271B673> ,
    <F6XRK5#SIP4060CC31942737EC> ;
  up:existence up:Predicted_Existence ;
  up:classifiedWith keyword:1185 ,
    go:0016422 ,
    go:0099122 ;
  up:sequence isoform:F6XRK5-1 ;
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  up:proteome <http://purl.uniprot.org/proteomes/UP000002280#Chromosome%201> .
citation:17495919 rdf:type up:Journal_Citation ;
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  up:author "Mikkelsen T.S." ,
    "Wakefield M.J." ,
    "Aken B." ,
    "Amemiya C.T." ,
    "Chang J.L." ,
    "Duke S." ,
    "Garber M." ,
    "Gentles A.J." ,
    "Goodstadt L." ,
    "Heger A." ,
    "Jurka J." ,
    "Kamal M." ,
    "Mauceli E." ,
    "Searle S.M." ,
    "Sharpe T." ,
    "Baker M.L." ,
    "Batzer M.A." ,
    "Benos P.V." ,
    "Belov K." ,
    "Clamp M." ,
    "Cook A." ,
    "Cuff J." ,
    "Das R." ,
    "Davidow L." ,
    "Deakin J.E." ,
    "Fazzari M.J." ,
    "Glass J.L." ,
    "Grabherr M." ,
    "Greally J.M." ,
    "Gu W." ,
    "Hore T.A." ,
    "Huttley G.A." ,
    "Kleber M." ,
    "Jirtle R.L." ,
    "Koina E." ,
    "Lee J.T." ,
    "Mahony S." ,
    "Marra M.A." ,
    "Miller R.D." ,
    "Nicholls R.D." ,
    "Oda M." ,
    "Papenfuss A.T." ,
    "Parra Z.E." ,
    "Pollock D.D." ,
    "Ray D.A." ,
    "Schein J.E." ,
    "Speed T.P." ,
    "Thompson K." ,
    "VandeBerg J.L." ,
    "Wade C.M." ,
    "Walker J.A." ,
    "Waters P.D." ,
    "Webber C." ,
    "Weidman J.R." ,
    "Xie X." ,
    "Zody M.C." ,
    "Baldwin J." ,
    "Abdouelleil A." ,
    "Abdulkadir J." ,
    "Abebe A." ,
    "Abera B." ,
    "Abreu J." ,
    "Acer S.C." ,
    "Aftuck L." ,
    "Alexander A." ,
    "An P." ,
    "Anderson E." ,
    "Anderson S." ,
    "Arachi H." ,
    "Azer M." ,
    "Bachantsang P." ,
    "Barry A." ,
    "Bayul T." ,
    "Berlin A." ,
    "Bessette D." ,
    "Bloom T." ,
    "Bloom T.'" ,
    "Boguslavskiy L." ,
    "Bonnet C." ,
    "Boukhgalter B." ,
    "Bourzgui I." ,
    "Brown A." ,
    "Cahill P." ,
    "Channer S." ,
    "Cheshatsang Y." ,
    "Chuda L." ,
    "Citroen M." ,
    "Collymore A." ,
    "Cooke P." ,
    "Costello M." ,
    "D'Aco K." ,
    "Daza R." ,
    "De Haan G." ,
    "DeGray S." ,
    "DeMaso C." ,
    "Dhargay N." ,
    "Dooley K." ,
    "Dooley E." ,
    "Doricent M." ,
    "Dorje P." ,
    "Dorjee K." ,
    "Dupes A." ,
    "Elong R." ,
    "Falk J." ,
    "Farina A." ,
    "Faro S." ,
    "Ferguson D." ,
    "Fisher S." ,
    "Foley C.D." ,
    "Franke A." ,
    "Friedrich D." ,
    "Gadbois L." ,
    "Gearin G." ,
    "Gearin C.R." ,
    "Giannoukos G." ,
    "Goode T." ,
    "Graham J." ,
    "Grandbois E." ,
    "Grewal S." ,
    "Gyaltsen K." ,
    "Hafez N." ,
    "Hagos B." ,
    "Hall J." ,
    "Henson C." ,
    "Hollinger A." ,
    "Honan T." ,
    "Huard M.D." ,
    "Hughes L." ,
    "Hurhula B." ,
    "Husby M.E." ,
    "Kamat A." ,
    "Kanga B." ,
    "Kashin S." ,
    "Khazanovich D." ,
    "Kisner P." ,
    "Lance K." ,
    "Lara M." ,
    "Lee W." ,
    "Lennon N." ,
    "Letendre F." ,
    "LeVine R." ,
    "Lipovsky A." ,
    "Liu X." ,
    "Liu J." ,
    "Liu S." ,
    "Lokyitsang T." ,
    "Lokyitsang Y." ,
    "Lubonja R." ,
    "Lui A." ,
    "MacDonald P." ,
    "Magnisalis V." ,
    "Maru K." ,
    "Matthews C." ,
    "McCusker W." ,
    "McDonough S." ,
    "Mehta T." ,
    "Meldrim J." ,
    "Meneus L." ,
    "Mihai O." ,
    "Mihalev A." ,
    "Mihova T." ,
    "Mittelman R." ,
    "Mlenga V." ,
    "Montmayeur A." ,
    "Mulrain L." ,
    "Navidi A." ,
    "Naylor J." ,
    "Negash T." ,
    "Nguyen T." ,
    "Nguyen N." ,
    "Nicol R." ,
    "Norbu C." ,
    "Norbu N." ,
    "Novod N." ,
    "O'Neill B." ,
    "Osman S." ,
    "Markiewicz E." ,
    "Oyono O.L." ,
    "Patti C." ,
    "Phunkhang P." ,
    "Pierre F." ,
    "Priest M." ,
    "Raghuraman S." ,
    "Rege F." ,
    "Reyes R." ,
    "Rise C." ,
    "Rogov P." ,
    "Ross K." ,
    "Ryan E." ,
    "Settipalli S." ,
    "Shea T." ,
    "Sherpa N." ,
    "Shi L." ,
    "Shih D." ,
    "Sparrow T." ,
    "Spaulding J." ,
    "Stalker J." ,
    "Stange-Thomann N." ,
    "Stavropoulos S." ,
    "Stone C." ,
    "Strader C." ,
    "Tesfaye S." ,
    "Thomson T." ,
    "Thoulutsang Y." ,
    "Thoulutsang D." ,
    "Topham K." ,
    "Topping I." ,
    "Tsamla T." ,
    "Vassiliev H." ,
    "Vo A." ,
    "Wangchuk T." ,
    "Wangdi T." ,
    "Weiand M." ,
    "Wilkinson J." ,
    "Wilson A." ,
    "Yadav S." ,
    "Young G." ,
    "Yu Q." ,
    "Zembek L." ,
    "Zhong D." ,
    "Zimmer A." ,
    "Zwirko Z." ,
    "Jaffe D.B." ,
    "Alvarez P." ,
    "Brockman W." ,
    "Butler J." ,
    "Chin C." ,
    "Gnerre S." ,
    "MacCallum I." ,
    "Graves J.A." ,
    "Ponting C.P." ,
    "Breen M." ,
    "Samollow P.B." ,
    "Lander E.S." ,
    "Lindblad-Toh K." ;
  skos:exactMatch pubmed:17495919 ;
  foaf:primaryTopicOf <https://pubmed.ncbi.nlm.nih.gov/17495919> ;
  dcterms:identifier "doi:10.1038/nature05805" ;
  up:date "2007"^^xsd:gYear ;
  up:name "Nature" ;
  up:volume "447" ;
  up:pages "167-177" .
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  rdf:predicate up:citation ;
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  faldo:reference isoform:F6XRK5-1 .
position:19763001335428398tt92 rdf:type faldo:Position ,
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  faldo:position 171 ;
  faldo:reference isoform:F6XRK5-1 .
<#_kb.F6XRK5_up.annotation_EF191A8F0B96AD22> rdf:type rdf:Statement ;
  rdf:subject <F6XRK5> ;
  rdf:predicate up:annotation ;
  rdf:object <F6XRK5#SIPDED804EDB1FB8BF8> ;
  up:attribution <F6XRK5#attribution-260F9275F08C92D1CF2D41553CB78263> .
<F6XRK5#SIP184323F34082C5B7> rdf:type up:Region_Annotation ;
  rdfs:comment "Disordered" ;
  up:range range:19763001335428398tt679tt721 .
range:19763001335428398tt679tt721 rdf:type faldo:Region ;
  faldo:begin position:19763001335428398tt679 ;
  faldo:end position:19763001335428398tt721 .
position:19763001335428398tt679 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 679 ;
  faldo:reference isoform:F6XRK5-1 .
position:19763001335428398tt721 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 721 ;
  faldo:reference isoform:F6XRK5-1 .
<#_kb.F6XRK5_up.annotation_1F99D93849050A21> rdf:type rdf:Statement ;
  rdf:subject <F6XRK5> ;
  rdf:predicate up:annotation ;
  rdf:object <F6XRK5#SIP184323F34082C5B7> ;
  up:attribution <F6XRK5#attribution-260F9275F08C92D1CF2D41553CB78263> .
<F6XRK5#SIP8A120C654AFAC4E0> rdf:type up:Compositional_Bias_Annotation ;
  rdfs:comment "Polar residues" ;
  up:range range:19763001335428398tt1tt33 .
range:19763001335428398tt1tt33 rdf:type faldo:Region ;
  faldo:begin position:19763001335428398tt1 ;
  faldo:end position:19763001335428398tt33 .
position:19763001335428398tt33 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 33 ;
  faldo:reference isoform:F6XRK5-1 .
<#_kb.F6XRK5_up.annotation_90BE97A79D2E8FC1> rdf:type rdf:Statement ;
  rdf:subject <F6XRK5> ;
  rdf:predicate up:annotation ;
  rdf:object <F6XRK5#SIP8A120C654AFAC4E0> ;
  up:attribution <F6XRK5#attribution-260F9275F08C92D1CF2D41553CB78263> .
<F6XRK5#SIPACA5A473A271B673> rdf:type up:Compositional_Bias_Annotation ;
  rdfs:comment "Basic and acidic residues" ;
  up:range range:19763001335428398tt119tt134 .
range:19763001335428398tt119tt134 rdf:type faldo:Region ;
  faldo:begin position:19763001335428398tt119 ;
  faldo:end position:19763001335428398tt134 .
position:19763001335428398tt119 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 119 ;
  faldo:reference isoform:F6XRK5-1 .
position:19763001335428398tt134 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 134 ;
  faldo:reference isoform:F6XRK5-1 .
<#_kb.F6XRK5_up.annotation_DE9250AE8C4CD1B5> rdf:type rdf:Statement ;
  rdf:subject <F6XRK5> ;
  rdf:predicate up:annotation ;
  rdf:object <F6XRK5#SIPACA5A473A271B673> ;
  up:attribution <F6XRK5#attribution-260F9275F08C92D1CF2D41553CB78263> .
<F6XRK5#SIP4060CC31942737EC> rdf:type up:Compositional_Bias_Annotation ;
  rdfs:comment "Polar residues" ;
  up:range range:19763001335428398tt679tt702 .
range:19763001335428398tt679tt702 rdf:type faldo:Region ;
  faldo:begin position:19763001335428398tt679 ;
  faldo:end position:19763001335428398tt702 .
position:19763001335428398tt702 rdf:type faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 702 ;
  faldo:reference isoform:F6XRK5-1 .
<#_kb.F6XRK5_up.annotation_3DB8BBD7698488A7> rdf:type rdf:Statement ;
  rdf:subject <F6XRK5> ;
  rdf:predicate up:annotation ;
  rdf:object <F6XRK5#SIP4060CC31942737EC> ;
  up:attribution <F6XRK5#attribution-260F9275F08C92D1CF2D41553CB78263> .
<#_kb.F6XRK5_up.classifiedWith_239F467843ABCFE3> rdf:type rdf:Statement ;
  rdf:subject <F6XRK5> ;
  rdf:predicate up:classifiedWith ;
  rdf:object keyword:1185 ;
  up:attribution <F6XRK5#attribution-9A3452CCFE716BE254A9C17482E9E16C> .
<#_kb.F6XRK5_up.classifiedWith_obo.GO_0016422> rdf:type rdf:Statement ;
  rdf:subject <F6XRK5> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0016422 ;
  up:attribution <F6XRK5#attribution-BCD67FFDCAB6DDEA2C9B27B77B8BED1D> .
<#_kb.F6XRK5_up.classifiedWith_obo.GO_0099122> rdf:type rdf:Statement ;
  rdf:subject <F6XRK5> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0099122 ;
  up:attribution <F6XRK5#attribution-BCD67FFDCAB6DDEA2C9B27B77B8BED1D> .
isoform:F6XRK5-1 rdf:type up:Simple_Sequence ;
  up:modified "2019-12-11"^^xsd:date ;
  up:version 3 ;
  up:mass 82322 ;
  up:md5Checksum "abc0334376a2956dc82491dc6b319b1f" ;
  rdf:value "MANENHGSPREEASLLSHSPGTSNQSQPSSPKPIRLVQDLPDATFSREPLISSFSLDELVQAGWEKCWSRRENRPYYFNRFTNQSLWEMPVLGQHDVISDPLGLNAAPMHSEAGVVETPVENKPRKRRLSEEQPSGNIVKKPKAEVPGTPSAQSVPSSPSVPGTPAIKLWGTSPEDKQQAALLRPTEVYWDLDIQTNAVIKQRGPSEVLPPHPEVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGPDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAAKRLIESRSASPDSRKVVKWNVEDTFSWLRKDHSASKDDYMDRLEHLRKQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAILKENNIPEEAEAAEVEQRLVYCYPVRLAVPSPPLPSVEMHMENNVACVRYKGEMVKVSRNFFSKLWLLYRYSCIDDSAFERFLPRVWCLLRRYQMMFGVGLYEGTGLQGSLPVHVFEALHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFYPLSGSFEANPPFCEELMDAMVSHFEKLLESSPEPLSFIVFIPEWRDPPTPALTRMERSRFKRHQLVLPAFDHEYRSGSQHICKKEELYYKAVHNTAVLFLQNDPGFAKWEPTPARLQELTTAYRQSGRSHGSTSGSSSTSSSSEAKDRDTGREQSTSRESNPT" .
<F6XRK5#attribution-BCD67FFDCAB6DDEA2C9B27B77B8BED1D> dcterms:creator <http://purl.uniprot.org/goa-projects/InterPro> ;
  up:evidence ECO:0007669 .
<F6XRK5#attribution-260F9275F08C92D1CF2D41553CB78263> up:evidence ECO:0000256 ;
  up:source <http://purl.uniprot.org/sam/MobiDB-lite> .
<F6XRK5#attribution-43317829F3EB1A5ACC8848C630C77581> up:evidence ECO:0000259 ;
  up:source <http://purl.uniprot.org/prosite/PS50020> .
<F6XRK5#attribution-6C065458B8CD0CEE95A07615F25AF768> up:evidence ECO:0000313 ;
  up:source <http://rdf.ebi.ac.uk/resource/ensembl.protein/ENSMODP00000017154.4> .
<http://rdf.ebi.ac.uk/resource/ensembl.protein/ENSMODP00000017154.4> up:database <http://purl.uniprot.org/database/Ensembl> .
<F6XRK5#attribution-9A3452CCFE716BE254A9C17482E9E16C> up:evidence ECO:0000313 ;
  up:source <http://purl.uniprot.org/proteomes/UP000002280> .