Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)A0A1I7UCK4[1245 - 1294]
Description
Feature keyDomain
Feature identifier
        10         20         30         40         50
MCVLFVPPAV IYSVRMDIFE ILYNNVFVLV QLILVSGRLI CCSNGCGREC
60 70 80 90 100
VAPIAKSFPI SGDKPIQPVS SSSSSNLPGS FQRLINAVSN IKSTHFNITP
110 120 130 140 150
IPPTIRNLAN SLFPTPSPIR PLPTTKVGQC PSPTGNKSIC SDQKQCGNDL
160 170 180 190 200
DCGSVDKCCP NACGSTCMEP LKATGCIHMV LAISKLKDRR LPNEYVPFCE
210 220 230 240 250
RNGRFSSIQC DIQFCWCVDV HYGSEIAGTK ISREQRRIHM CREPRLCTKK
260 270 280 290 300
CHNQCTHGHV MDIFGCPVPS CLCLDICNNV KCENKWEQCQ LVEPDCANPP
310 320 330 340 350
CLPVPRCLLN PCRTGPPSRL SNGITALCSN DKDCPEGTCS KIGYNGLGFC
360 370 380 390 400
CSGPASSTRD GRCPSQSADK LKCILYPENS CHSDHECSED EKCCFNGCTL
410 420 430 440 450
SCTQPEDYVI RKPVKPVTEP IMHYQPGDVE KYNKGHLSSL VADCADVIPA
460 470 480 490 500
NISCTTECHS DSQCVGMKRC CRQGCSTNCM YPVRSTPCFH LALTAELYSL
510 520 530 540 550
RNAMKCDRAG NFEQFQCDDE GCFCVDIATG EELPGSRAIG RKPNCESRNP
560 570 580 590 600
CEPLVCKVAC PFGFEKGANS CPTCKCKNPC EEVKCPQGSV CVMSSVQCYQ
610 620 630 640 650
TGNCASQPRC ILNFCPTGEP YISSIGNVES CTKDEECPSS THWCHRLGLA
660 670 680 690 700
SGGICCPSPS RVRHAGYCPT ISISLDAKMC RVSCKVDDDC NGHQKCCFDG
710 720 730 740 750
CGATCRDITT PLVEISKEIL EKAGTCISEQ RVLCNRLEKN TCEYDTDCAG
760 770 780 790 800
VAKCCDDGCV KACAYPLQTS KCLVRKTNLQ KMGQMDLIKC RPDGSFEQIQ
810 820 830 840 850
CDIEFCWCVD EEGNYVDGTR TGEDITPNCP EPCEKLECGS IGCEYGHKKD
860 870 880 890 900
NRGCSTCECV DPCEGVACPD DSLCIPTTVP CVTKPCPTIP RCVINPCPIS
910 920 930 940 950
ESIKNETTLH LKKCYRGNDC YDPMMTTHCS MLTQDFGFCC TGETSEIHTG
960 970 980 990 1000
SCPKITELNT AKVEKCVQEC KTDSDCNQSS KCCWNGCGLT CVTSFNNRQI
1010 1020 1030 1040 1050
VPVLQTASES HFGECLNVAP LGAFCLQRPT IADCKNDDDC PSLYKCCSDG
1060 1070 1080 1090 1100
CVMRCTQPNR APLCIHQRVS ALAIADNEGS DSNEKDSEIF VPDCDSSGNF
1110 1120 1130 1140 1150
DEVQSHFGLM WCVDRLGREI SGTKSTRVPN CDHPRPCPTR VCAEQCSYGF
1160 1170 1180 1190 1200
KSDNEGCPIC DCIAPCEFIN CPAGNVCRMI PVKCTTEECR PVAKCIPNMC
1210 1220 1230 1240 1250
GVGEPLSHDH ALLATCSSIS PCPAGFHCKN SGYSDISFCC STPELSQQSL
1260 1270 1280 1290 1300
KCPVIPLMIA SVDGSSCVVG CRHHYDCTHS SCCFNGCGTS CQFETRQSPI
1310 1320 1330 1340 1350
KPIKISSSKP SKTTRKPILS SLKIEKKASK IENVIVEHHP LRPVSPVLAK
1360 1370 1380 1390 1400
LGTCPKLLIN PGCTEQCNRD SDCHGFLKCC TASCGTMCSA PRIATACIHR
1410 1420 1430 1440 1450
LIAFESNVAS EIVNLIIPPV QCTPEGLFRR YQCDARINQC WCVDVATGIE
1460 1470 1480 1490 1500
EIGTRMFTIG LQPPDCDLPK SCSTQCEQSR CPYGIKTDGG GCPANGVCEC
1510 1520 1530 1540 1550
NNICSSFNCP LNMECALRRV ECTSNPCPDV PFCVEVQCPI PQRDLFRNVI
1560 1570 1580 1590 1600
LCENDGGCGK NSKCVTNPKT ERGICCHQKL IQSSVLNLIS PAIVASGQED
1610 1620 1630 1640 1650
FETTTEIVQK GNGPVVVEAI PMSLSTNCTT MRIALEYLHQ NGAILKSPLP
1660 1670 1680 1690 1700
MCSKNGNYEK TQCDNKRCWC VDELSGEEIH GTRKKKTKNA CKSQSMCFSK
1710 1720 1730 1740 1750
CSANLCPYGL LLDSIGCPRS ECICKSACEH VDCPNGQVCI LRRADCPDKW
1760 1770 1780 1790 1800
CLPVPTCEKS PCNSGLRPLI ETRTRQQYSC TQNTVCPMGY YCTAFDDNMH
1810 1820 1830 1840 1850
GVCCPGANSI KSIGEHNGLS CPHGDPFSSL SDGSPLSCTV LTNGCPATHY
1860 1870 1880 1890 1900
CSTMPGRKSG ICCVSKRYVC NLQRDSGPCS ALVTRFFYSS LTHSCSSFDY
1910 1920 1930 1940 1950
GGCSGNLNNF ATRDDCDNFC AGIGLDLSSP YDHANAPQPT ESYQIAFSLT
1960 1970 1980 1990 2000
GGKIPSSKME DAEIQLINML VERFKIPRGS IEDVILRDDN TVKFTIRDID
2010 2020 2030 2040 2050
ARRFAREVSE KVSTGELSMT LAGQKLIAEP HTLTALHVSH EHGTRNTTQV
2060 2070 2080 2090 2100
ILYAILLASA IFLLCVICLV CFSCFCYYRN QPKDRSQTPS NTTAITENRS
2110 2120 2130 2140
RQSGLRRVFS RDDVSVCSDF NRPPMHDISM LNRERERPPR SQSWLSIG
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again