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<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)A0A2K5LJC3[1524 - 1565]
Description
Feature keyCompositional bias
Feature identifier
        10         20         30         40         50
MGNSESQYTL QGSKNHSNTI TGAKQIPCSL KIRGIHAKEE KSLHGWGHGS
60 70 80 90 100
SGAGYKSRSL ARSCLSHFKS NQPYASRLGG STCKVSRGVA YSTHRTNAPG
110 120 130 140 150
KDFQGISAAF STENGFHSVG HEPADNHITS RDCNGHLLNC YGRNESVAST
160 170 180 190 200
PPGEDRKSPR VLIKTLGKLD GCLRVEFHNG GNPSKVPAED SSEPVQLLRY
210 220 230 240 250
SPTLASETSP VPEARRESSA DSLPSHRPSP TDSRLRSSKG SSLSSESSWY
260 270 280 290 300
DSPWGNAGEL SEAEGSFLAP GMPDPSLHAS FPPGDAKKPF NQSSSLSSLR
310 320 330 340 350
ELYKDANLGS LSPSGIRLSD EYMGTHASLS NRVSFASDID VPSRVAHRDP
360 370 380 390 400
VQYSSFTLPC RKPKALVEDT AKKDSLKARM RRISDWTGSL SRKKRKLQEP
410 420 430 440 450
RSKEGSDYFD SRSDGLNTDV QGPSQASAFL WSGGSAQILS QRSESTHAIG
460 470 480 490 500
SDPLRQNIYE NFMRELEMSR TNTENIETST ETAESSSESL SSLEQLDLLF
510 520 530 540 550
EKEQGVVRKA GWLFFKPLVT VQKERKLELV ARRKWKQYWV TLKGCTLLFY
560 570 580 590 600
ETYGKNSMDQ SSAPRCALFA EDSIVQSVPE HPKKENVFCL SNSFGDVYLF
610 620 630 640 650
QATSQTDLEN WVTAVHSACA SLFAKKHGKE DTLRLLKNQT KNLLQKIDMD
660 670 680 690 700
SKMKKMAELQ LSIVSDPKNR KAIENQIQQW EQNLEKFHMD LFRMRCYLAS
710 720 730 740 750
LQGGELPNPK SLLAAASRPS KLALGRLGIL SVSSFHALVC SRDDSALRKR
760 770 780 790 800
TLSLTQRGRN KKGIFSSLKG LDTLARKGKE KRPSITQIFD LSVSHGFSGT
810 820 830 840 850
QLPQNSNNYS EVDELLHMYG STVDSVPRDN AWEIQTYVHF QDNHGVTVGI
860 870 880 890 900
KPEHRVEDIL TLACKMRQLE PSHYGLQLRK LVDDNVEYCI PAPYEYMQEQ
910 920 930 940 950
VYDEIEVFPL NVYDVQLTKT GSVCDFGFAV TAQVDEHQHL SRIFVSDVLP
960 970 980 990 1000
DGLAYGEGLR KGNEIMTLNG EAVSDLDLKQ MEALFSEKSV GLTLIARPPD
1010 1020 1030 1040 1050
TKATLCTSWS DSDLFSRDQK SLLPPPNQSQ LLEEFLDNFK KNTANDFSNV
1060 1070 1080 1090 1100
PDITTGLKRS QTDGTLDQVS HREKMEQTFR SAEQITALCR SFNDTQANGM
1110 1120 1130 1140 1150
EGPRESQDPP PRPLARHLSD ADRLRKVIQE LVDTEKSYVK DLSCLFELYL
1160 1170 1180 1190 1200
EPLQNETFLT QDEMESLFGS LPEMLEFQKV FLETLEDGIS ASSDFNTLET
1210 1220 1230 1240 1250
PSQFRKLLFS LGGSFLYYAD HFKLYSGFCA NHIKVQKVLE RAKTDKAFKA
1260 1270 1280 1290 1300
FLDARNPTKQ HSSTLESYLI KPVQRVLKYP LLLKELVSLT DQESEEHYHL
1310 1320 1330 1340 1350
TEALKAMEKV ASHINEMQKI YEDYGTVFDQ LVAEQSGTEK EVTELSMGEL
1360 1370 1380 1390 1400
LMHSTVSWLN PFLSLGKARK DLELTVFVFK RAVILVYKEN CKLKKKLPSN
1410 1420 1430 1440 1450
SRPAHNSADL DPFKFRWLIP ISALQVRLGN PAGTENNSIW ELIHTKSEIE
1460 1470 1480 1490 1500
GRPETIFQLC CSDSESKTNI VKVIRSILRE NFRRHIKCEL PLEKTCKDRL
1510 1520 1530 1540 1550
VPLKNRVPVS AKLASSRSLK VLKNSSSNEW TGETGKGTLL DSDEGSLSSG
1560 1570 1580 1590 1600
TQSSGCPTAE GRQDSKTASP GKYPHPGLAD FADNLIKESD ILSDEDDDHH
1610 1620 1630 1640 1650
QTLKRGSPTK DIEIQFQRLR ISEDPDVHPE AEQQPGPEAG EGQKGGEQPK
1660 1670 1680 1690 1700
LVRGHFCPIK RKANSTKRDR GTLLKAQLRH QSLDSQSENA TIDLNSVLER
1710 1720
EFSVQSLTSV VNEECFYETE SHGKS
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Main funding by: National Institutes of Health

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