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<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)F7DGV6[1 - 104]
Description
Feature keyDomain
Feature identifier
        10         20         30         40         50
GCSAPIRGNY ILLRAQNQVL KRAVVDEQAN STALKEQLKM KDQSLRKQQQ
60 70 80 90 100
EMDSLTFRNQ QLAKRVELLQ EELCLMEAKG KKTKKNMDAA QLSQEQKSVF
110 120 130 140 150
DEDLQKKIEE NERLHIQFFE ASEKHRLVES ELKSRLQELE TSTAQHQAVV
160 170 180 190 200
DGLTHKYMET IEKLQSDKAK LEVKCQALER EAKECRLRTE ECQNQLKTLH
210 220 230 240 250
IDLSSRLDDS LGIINEKVPF NDTRTSQLNA LNVPVHNKRN QLKARELASQ
260 270 280 290 300
GLSFVRDLVT ALLNFHTYTE QRVQIFPIDS AIDVISPLNK KFSEYLHENA
310 320 330 340 350
SYVRPLEDGM LQLFESVTED TVTVLETAVK LKIFSENFAS YVCFLQKILP
360 370 380 390 400
YQLKSLEEES EFSSCTSALL ARNVELHNDM KKITAAFDKL KTYITLLALP
410 420 430 440 450
STKPEGLLRS NYGTILTQIS EALHRLHDIT KELSKHYNNK AALEQELPAA
460 470 480 490 500
TDKLKTTNDC ILSSLAALTN VTSKIATFFG NNLDYFISSL SYGPKGGQGF
510 520 530 540 550
TNPVSAEMML EYKKKAAQYM NSLKKPCPDS VPYEEALMNR RVLLSSTESR
560 570 580 590 600
EGLAQQVQQS LEKIGKLEQE KEHWMLEAQL SKIKLEKETH RIAALIKSTE
610 620 630 640 650
MGQLAEVPHD NAFFLLNAGE HGKANSTETK STSLIGMLTG TTEDLQDCDS
660 670 680 690 700
TEELIKNHYM ARIAELTTHL QQADSKSVHL YAECRALAKR LALADKSNRS
710 720 730 740 750
LTEETKSAVQ SISKLQDELI TTKRSYEDQL SMMSDHLCIM NETLSKQREE
760
IDTLKMATKV DLRSTCHCP
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Main funding by: National Institutes of Health

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