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<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)H2NFF1[76 - 165]
Description
Feature keyDomain
Feature identifier
        10         20         30         40         50
MTGAGELRRE EPPPQPSAGL RSRESGARSA GGWERAERGR GAAARPTTGP
60 70 80 90 100
PXXXXXXXXX XXANQVSPLA SPAARPEDVG TSLYFVNDSL QQVTFSSSVG
110 120 130 140 150
VVVPCPAAGS PSAALRWYLA TGDDIYDVPH IRHVHANGTL QLYPFSPSAF
160 170 180 190 200
NSFIHDNDYF CTAENAAGKI RSPNIRVKAV FREPYTVRVE DQRSMRGNVA
210 220 230 240 250
VFKCLIPSSV QEYVSVVSWE KDTVSIIPGE RAGPGGLYIS DVQKEDALST
260 270 280 290 300
YRCITKHKYS GETRQSNGAR LSVTDPAESI PTILDGFHSQ EVWAGHTVEL
310 320 330 340 350
PCTASGYPIP AIRWLKDGRP LPADSRWTKR ITGLTISDLR TEDSGTYICE
360 370 380 390 400
VTNTFGSAEA TGILMVIDPL HVALTPKKLK TGIGSTVILS CALTGSPEFT
410 420 430 440 450
IRWYRNTELV LPDEAISIRG LSNETLLITS AQKSHSGAYQ CFATRKAQTA
460 470 480 490 500
QDFAIIALED GTPRIVSSFS EKVVNPGEQF SLMCAAKGAP PPTVTWALDD
510 520 530 540 550
EPIVRDGSHR TNQYTMSDGT TISHMNVTGP QIRDGGVYRC TARNSVGSAE
560 570 580 590 600
YQARINVRGP PSIRAMRNIT AVAGRDTLIN CRVIGYPYYS IKWYKDALLL
610 620 630 640 650
PDNHRQVVFE NGTLKLTDVQ KGMDEGEYLC SVLIQPQLSI SQSVHVAVKV
660 670 680 690 700
PPLIQPFEFP PASIGQLLYI PCVVSSGDMP IRITWRKDGQ VIISGSGVTI
710 720 730 740 750
ESKEFMSSLQ ISSVSLKHNG NYTCIASNAA ATVSRERQLI VRVPPRFVVQ
760 770 780 790 800
PNNQDGIYGK AGVLNCSVDG YPPPKVMWKH AKGSGNPQQY HPVPLTGRIQ
810 820 830 840 850
ILPNSSLLIR HVLEEDIGYY LCQASNGVGT DISKSMFLTV KIPAMITSHP
860 870 880 890 900
NTTIAIKGHA KELNCTARGE RPIIIRWEKG DTVIDPDRVM RYTITTKDNG
910 920 930 940 950
DEVISTLKLK PADRGDSVFF SCHAINSYGE DRGLIHSLTL EPPDPPELEI
960 970 980 990 1000
REVKARSMNL RWTQRFDGNS IITGFDIEYK NKSDSWDFKQ STRNISPTIN
1010 1020 1030 1040 1050
QANIVDLHPA SVYSIRMYSF NKIGRSEPSK ELTISTEEAA PDGPPMDVTL
1060 1070 1080 1090 1100
QPVTSQSIQV TWKAPKKELQ NGVIRGYQIG YRENSPGSNG QYSIVEMKAT
1110 1120 1130 1140 1150
GDSEVYTLDN LKKFAQYGVV VQAFNRAGTG PSSSEINATT LEDVPSQPPE
1160 1170 1180 1190 1200
NVRALSITSD VAVISWSEPP RSTLNGVLKG YRVIFWSLYV DGEWGEMQNI
1210 1220 1230 1240 1250
TTTRERVELR GMEKFTNYSV QVLAYTQAGD GVRSSVLYIQ TKEDVPGPPA
1260 1270 1280 1290 1300
GIKAVPSSAS SVVVSWLPPT KPNGVIRKYT IFCSSPGSGQ PAPSEYETSP
1310 1320 1330 1340 1350
EQLFYRIAHL NRGQQYLLWV AAVTSAGRGN SSEKVTIEPA GKAPAKIISF
1360 1370 1380 1390 1400
GGTVTTPWMK DVRLPCNSVG DPAPAVKWTK DSEDSAIPVS MDGHRIIHTN
1410 1420 1430 1440 1450
GTLLLRAVKA EDSGYYTCTA TNTGGFDTII VNLLVQVPPD QPRLTVSKTS
1460 1470 1480 1490 1500
ASSITLTWIP GDNGGSSIRG FMLQYSVDNS EEWKDVFISS SERSFKLDSL
1510 1520 1530 1540 1550
KCGTWYKVKL AAKNSVGSGR ISEIIEAKTH GREPSFSKDQ HLFTHINSTH
1560 1570 1580 1590 1600
ARLNLQGWNN GGCPITAIVL EYRPKGTWAW QGLRANSSGE VFLTELREAT
1610 1620 1630 1640 1650
WYELRMRACN SAGCGNETAQ FATLDYDGST IPPIKSAQGE GDDVKKLFTI
1660 1670 1680 1690 1700
GCPVILATLG VALLFIVRKK RKEKRLKRLR DAKSLAEMLI SKNNRSFDTP
1710 1720 1730 1740 1750
VKGPPQGPRL HIDIPRVQLL IEDKEGIKQL GDDKATIPVT DAEFSQAVNP
1760 1770 1780 1790 1800
QSFCTGVSLH HPALIQSTGP LIDMSDIRPG TNPVSRKNVK SAHSTRNRYS
1810 1820 1830 1840 1850
SQWTLTKCQA STPARTLTSD WRTVGSQHGV TVTESDSYSA SLSQDTDKGR
1860 1870 1880 1890 1900
NSMVSTESAS STYEELARAY EHAKLEEQLQ HAKFEITECF ISDSSSDQMT
1910 1920 1930 1940 1950
TGTNENADSM TSMSTPSEPG ICRFTASPPK PQDADRGKNV AVPIPHRANK
1960 1970 1980 1990 2000
SDYCNLPLYA KSEAFFRKAD GREPCPVVPP REASIRNLAR TYHTQARHLT
2010 2020 2030 2040 2050
LDPASKPLGL PHPGAPAAAS TATLPQRTLA MPAPPAGTAP PAPGPTPAEP
2060 2070 2080 2090 2100
PTAPSAAPPA PSTEPPRAGG PHTKMGGSRD SLLEMSTSRV GRSQKQGAGP
2110
TPNPTPLVXX XXALFIFN
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