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<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)P19263[1 - 745]
Description
Feature key
Feature identifier
        10         20         30         40         50
MTTTIGSPQM LANEERLSNE MHALKNRSEQ NGQEQQGPVK NTQLHGPSAT
60 70 80 90 100
DPETTATQKE SLEMVPKDTS AATMTSAPPP ALPHVEINQV SLALVIRNLT
110 120 130 140 150
VFTMKELAQY MKTNVHTQAN EPNSAKKIRF LQLIIFLRTQ FLKLYVLVKW
160 170 180 190 200
TRTIKQNNFH VLIDLLNWFR TTNMNVNNCI WALKSSLNSM TNAKLPNVDL
210 220 230 240 250
VTALEVLSLG RPNLPTHNFK LSGVSNSMDM VDGMAKVPIG LILQRLKDLN
260 270 280 290 300
LTVSIKIALM NIPKPLNSYH IKNGRIYFTV PNEFEIQLST VNRQSPLFFV
310 320 330 340 350
DLKLLFNTEA EQTVSAVTEA TSTNGDSENN EENSSSNGNN LPLNKPRLEK
360 370 380 390 400
LINEILLKSN DPLLSLYNFL HKYVLTLQLY MVHREFLKLA NGGKFSKSNL
410 420 430 440 450
IHNYDSKKST ITVRYWLNGK MDSKGKITIG IQRTTESLIL KWDNQSASRA
460 470 480 490 500
KNMPVIYNNI VSNIEGILDE IMFNHARIIR SELLARDIFQ EDEENSDVLL
510 520 530 540 550
FQLPTTCVSM APIQLKIDLL SGQFYFRNPT PLLSNYASKI NRAEGPEELA
560 570 580 590 600
RILQQLKLDK IIHVLTTMFE NTGWSCSRII KIDKPIRTQV NTGGESVVKK
610 620 630 640 650
EDNKYAIAGN STTNSDVSLL LQRDLFIRLP HWPLNWYLIL SIISSKTSCV
660 670 680 690 700
VEKRIGKIVS QRGKWNLKYL DNSNVMTVKL ESITYQKIMI LQRTILNRII
710 720 730 740 750
NHMLIDSLNQ LEIRNKICSS EMINEQKLPQ YIIQGSNTND NISIITLELE
760 770 780 790 800
SFLEGSKALN SILESSMFLR IDYSNSQIRL YAKFKRNTMM IQCQIDKLYI
810 820 830 840 850
HFVQEEPLAF YLEESFTNLG IIVQYLTKFR QKLMQLVVLT DVVERLHKNF
860 870 880 890 900
ESENFKIIAL QPNEISFKYL SNNDEDDKDC TIKISTNDDS IKNLTVQLSP
910 920 930 940 950
SNPQHIIQPF LDNSKMDYHF IFSYLQFTSS LFKALKVILN ERGGKFHESG
960 970 980 990 1000
SQYSTMVNIG LHNLNEYQIV YYNPQAGTKI TICIELKTVL HNGRDKIQFH
1010 1020 1030 1040 1050
IHFADVAHIT TKSPAYPMMH QVRNQVFMLD TKRLGTPESV KPANASHAIR
1060 1070 1080
LGNGVACDPS EIEPILMEIH NILKVDSNSS SS
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