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<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)P46100-4
Description
Feature key
Feature identifier
        10         20         30         40         50
MTAEPMSESK LNTLVQKLHD FLAHSSEESE ETSSPPRLAM NQNTDKISGS
60 70 80 90 100
GSNSDMMENS KEEGTSSSEK SKSSGSSRSK RKPSIVTKYV ESDDEKPLDD
110 120 130 140 150
ETVNEDASNE NSENDITMQS LPKEDGLHGI VSCTACGQQV NHFQKDSIYR
160 170 180 190 200
HPSLQVLICK NCFKYYMSDD ISRDSDGMDE QCRWCAEGGN LICCDFCHNA
210 220 230 240 250
FCKKCILRNL GRKELSTIMD ENNQWYCYIC HPEPLLDLVT ACNSVFENLE
260 270 280 290 300
QLLQQNKKKI KVDSEKSNKV YEHTSRFSPK KTSSNCNGEE KKLDDSCSGS
310 320 330 340 350
VTYSYSALIV PKEMIKKAKK LIETTANMNS SYVKFLKQAT DNSEISSATK
360 370 380 390 400
LRQLKAFKSV LADIKKAHLA LEEDLNSEFR AMDAVNKEKN TKEHKVIDAK
410 420 430 440 450
FETKARKGEK PCALEKKDIS KSEAKLSRKQ VDSEHMHQNV PTEEQRTNKS
460 470 480 490 500
TGGEHKKSDR KEEPQYEPAN TSEDLDMDIV SVPSSVPEDI FENLETAMEV
510 520 530 540 550
QSSVDHQGDG SSGTEQEVES SSVKLNISSK DNRGGIKSKT TAKVTKELYV
560 570 580 590 600
KLTPVSLSNS PIKGADCQEV PQDKDGYKSC GLNPKLEKCG LGQENSDNEH
610 620 630 640 650
LVENEVSLLL EESDLRRSPR VKTTPLRRPT ETNPVTSNSD EECNETVKEK
660 670 680 690 700
QKLSVPVRKK DKRNSSDSAI DNPKPNKLPK SKQSETVDQN SDSDEMLAIL
710 720 730 740 750
KEVSRMSHSS SSDTDINEIH TNHKTLYDLK TQAGKDDKGK RKRKSSTSGS
760 770 780 790 800
DFDTKKGKSA KSSIISKKKR QTQSESSNYD SELEKEIKSM SKIGAARTTK
810 820 830 840 850
KRIPNTKDFD SSEDEKHSKK GMDNQGHKNL KTSQEGSSDD AERKQERETF
860 870 880 890 900
SSAEGTVDKD TTIMELRDRL PKKQQASAST DGVDKLSGKE QSFTSLEVRK
910 920 930 940 950
VAETKEKSKH LKTKTCKKVQ DGLSDIAEKF LKKDQSDETS EDDKKQSKKG
960 970 980 990 1000
TEEKKKPSDF KKKVIKMEQQ YESSSDGTEK LPEREEICHF PKGIKQIKNG
1010 1020 1030 1040 1050
TTDGEKKSKK IRDKTSKKKD ELSDYAEKST GKGDSCDSSE DKKSKNGAYG
1060 1070 1080 1090 1100
REKKRCKLLG KSSRKRQDCS SSDTEKYSMK EDGCNSSDKR LKRIELRERR
1110 1120 1130 1140 1150
NLSSKRNTKE IQSGSSSSDA EESSEDNKKK KQRTSSKKKA VIVKEKKRNS
1160 1170 1180 1190 1200
LRTSTKRKQA DITSSSSSDI EDDDQNSIGE GSSDEQKIKP VTENLVLSSH
1210 1220 1230 1240 1250
TGFCQSSGDE ALSKSVPVTV DDDDDDNDPE NRIAKKMLLE EIKANLSSDE
1260 1270 1280 1290 1300
DGSSDDEPEE GKKRTGKQNE ENPGDEEAKN QVNSESDSDS EESKKPRYRH
1310 1320 1330 1340 1350
RLLRHKLTVS DGESGEEKKT KPKEHKEVKG RNRRKVSSED SEDSDFQESG
1360 1370 1380 1390 1400
VSEEVSESED EQRPRTRSAK KAELEENQRS YKQKKKRRRI KVQEDSSSEN
1410 1420 1430 1440 1450
KSNSEEEEEE KEEEEEEEEE EEEEEEDEND DSKSPGKGRK KIRKILKDDK
1460 1470 1480 1490 1500
LRTETQNALK EEEERRKRIA EREREREKLR EVIEIEDASP TKCPITTKLV
1510 1520 1530 1540 1550
LDEDEETKEP LVQVHRNMVI KLKPHQVDGV QFMWDCCCES VKKTKKSPGS
1560 1570 1580 1590 1600
GCILAHCMGL GKTLQVVSFL HTVLLCDKLD FSTALVVCPL NTALNWMNEF
1610 1620 1630 1640 1650
EKWQEGLKDD EKLEVSELAT VKRPQERSYM LQRWQEDGGV MIIGYEMYRN
1660 1670 1680 1690 1700
LAQGRNVKSR KLKEIFNKAL VDPGPDFVVC DEGHILKNEA SAVSKAMNSI
1710 1720 1730 1740 1750
RSRRRIILTG TPLQNNLIEY HCMVNFIKEN LLGSIKEFRN RFINPIQNGQ
1760 1770 1780 1790 1800
CADSTMVDVR VMKKRAHILY EMLAGCVQRK DYTALTKFLP PKHEYVLAVR
1810 1820 1830 1840 1850
MTSIQCKLYQ YYLDHLTGVG NNSEGGRGKA GAKLFQDFQM LSRIWTHPWC
1860 1870 1880 1890 1900
LQLDYISKEN KGYFDEDSMD EFIASDSDET SMSLSSDDYT KKKKKGKKGK
1910 1920 1930 1940 1950
KDSSSSGSGS DNDVEVIKVW NSRSRGGGEG NVDETGNNPS VSLKLEESKA
1960 1970 1980 1990 2000
TSSSNPSSPA PDWYKDFVTD ADAEVLEHSG KMVLLFEILR MAEEIGDKVL
2010 2020 2030 2040 2050
VFSQSLISLD LIEDFLELAS REKTEDKDKP LIYKGEGKWL RNIDYYRLDG
2060 2070 2080 2090 2100
STTAQSRKKW AEEFNDETNV RGRLFIISTK AGSLGINLVA ANRVIIFDAS
2110 2120 2130 2140 2150
WNPSYDIQSI FRVYRFGQTK PVYVYRFLAQ GTMEDKIYDR QVTKQSLSFR
2160 2170 2180 2190 2200
VVDQQQVERH FTMNELTELY TFEPDLLDDP NSEKKKKRDT PMLPKDTILA
2210 2220 2230 2240 2250
ELLQIHKEHI VGYHEHDSLL DHKEEEELTE EERKAAWAEY EAEKKGLTMR
2260 2270 2280 2290 2300
FNIPTGTNLP PVSFNSQTPY IPFNLGALSA MSNQQLEDLI NQGREKVVEA
2310 2320 2330 2340 2350
TNSVTAVRIQ PLEDIISAVW KENMNLSEAQ VQALALSRQA SQELDVKRRE
2360 2370 2380 2390 2400
AIYNDVLTKQ QMLISCVQRI LMNRRLQQQY NQQQQQQMTY QQATLGHLMM
2410 2420 2430 2440 2450
PKPPNLIMNP SNYQQIDMRG MYQPVAGGMQ PPPLQRAPPP MRSKNPGPSQ

GKSM
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