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<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)P46100-6
Description
Feature key
Feature identifier
        10         20         30         40         50
MTAEPMSESK LNTLVQKLHD FLAHSSEESE ETSSPPRLAM NQNTDKISGS
60 70 80 90 100
GSNSDMMENS KEEGTSSSEK SKSSGSSRSK RKPSIVTKYV ESDDEKPLDD
110 120 130 140 150
ETVNEDASNE NSENDITMQS LPKDGLHGIV SCTACGQQVN HFQKDSIYRH
160 170 180 190 200
PSLQVLICKN CFKYYMSDDI SRDSDGMDEQ CRWCAEGGNL ICCDFCHNAF
210 220 230 240 250
CKKCILRNLG RKELSTIMDE NNQWYCYICH PEPLLDLVTA CNSVFENLEQ
260 270 280 290 300
LLQQNKKKIK VDSEKSNKVY EHTSRFSPKK TSSNCNGEEK KLDDSCSGSV
310 320 330 340 350
TYSYSALIVP KEMIKKAKKL IETTANMNSS YVKFLKQATD NSEISSATKL
360 370 380 390 400
RQLKAFKSVL ADIKKAHLAL EEDLNSEFRA MDAVNKEKNT KEHKVIDAKF
410 420 430 440 450
ETKARKGEKP CALEKKDISK SEAKLSRKQV DSEHMHQNVP TEEQRTNKST
460 470 480 490 500
GGEHKKSDRK EEPQYEPANT SEDLDMDIVS VPSSVPEDIF ENLETAMEVQ
510 520 530 540 550
SSVDHQGDGS SGTEQEVESS SVKLNISSKD NRGGADCQEV PQDKDGYKSC
560 570 580 590 600
GLNPKLEKCG LGQENSDNEH LVENEVSLLL EESDLRRSPR VKTTPLRRPT
610 620 630 640 650
ETNPVTSNSD EECNETVKEK QKLSVPVRKK DKRNSSDSAI DNPKPNKLPK
660 670 680 690 700
SKQSETVDQN SDSDEMLAIL KEVSRMSHSS SSDTDINEIH TNHKTLYDLK
710 720 730 740 750
TQAGKDDKGK RKRKSSTSGS DFDTKKGKSA KSSIISKKKR QTQSESSNYD
760 770 780 790 800
SELEKEIKSM SKIGAARTTK KRIPNTKDFD SSEDEKHSKK GMDNQGHKNL
810 820 830 840 850
KTSQEGSSDD AERKQERETF SSAEGTVDKD TTIMELRDRL PKKQQASAST
860 870 880 890 900
DGVDKLSGKE QSFTSLEVRK VAETKEKSKH LKTKTCKKVQ DGLSDIAEKF
910 920 930 940 950
LKKDQSDETS EDDKKQSKKG TEEKKKPSDF KKKVIKMEQQ YESSSDGTEK
960 970 980 990 1000
LPEREEICHF PKGIKQIKNG TTDGEKKSKK IRDKTSKKKD ELSDYAEKST
1010 1020 1030 1040 1050
GKGDSCDSSE DKKSKNGAYG REKKRCKLLG KSSRKRQDCS SSDTEKYSMK
1060 1070 1080 1090 1100
EDGCNSSDKR LKRIELRERR NLSSKRNTKE IQSGSSSSDA EESSEDNKKK
1110 1120 1130 1140 1150
KQRTSSKKKA VIVKEKKRNS LRTSTKRKQA DITSSSSSDI EDDDQNSIGE
1160 1170 1180 1190 1200
GSSDEQKIKP VTENLVLSSH TGFCQSSGDE ALSKSVPVTV DDDDDDNDPE
1210 1220 1230 1240 1250
NRIAKKMLLE EIKANLSSDE DGSSDDEPEE GKKRTGKQNE ENPGDEEAKN
1260 1270 1280 1290 1300
QVNSESDSDS EESKKPRYRH RLLRHKLTVS DGESGEEKKT KPKEHKEVKG
1310 1320 1330 1340 1350
RNRRKVSSED SEDSDFQESG VSEEVSESED EQRPRTRSAK KAELEENQRS
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