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<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)Q8IRW8[1895 - 1935]
Description
Feature keyZinc finger
Feature identifier
        10         20         30         40         50
MNIPKVTTSL GAAEKAKPER VASVAAAAFN AVSLQKRSGD DTATPAEDPT
60 70 80 90 100
RKKAKTELLL GTGTAAPSLP AKASSTAPQQ LLYQRSGQQA KAQVKAASEP
110 120 130 140 150
QDVETADGVW DARDQQIIVC NFGSGTEMGA IKAEDADKQS EYRISTPRNS
160 170 180 190 200
QSNPLLHRNT AFTSFTKKEG ASSSASSSSS TASVISIEPS GSGQDHAENS
210 220 230 240 250
GKSEDLDYVL MPASGADSST SVGNSTGTGT PAGTPIGATT STIILNANNG
260 270 280 290 300
TAGVSGAGTT TILTQKSGHT NYNIFNTTAT GSQTPTTTLL NRVNLHPKMK
310 320 330 340 350
TQLMVNAKKL SEVTQTTAKV SIGNKTISVP LLKPLMSASG AATAGGATIV
360 370 380 390 400
ESKQLLQPGG QVTTVMSAAQ QSGGQQVHPH VHSHAHHNFT KLIKRGPKNS
410 420 430 440 450
GTIVSFSGLQ IKPANTKIVA TKVVSKKMLQ LQQHQQQIQQ QQQLQQLQVT
460 470 480 490 500
SGGGLAPPTG SIVTITTTNP SQTYAMVQDS ATVGPAAHSE DDAPAPRKIT
510 520 530 540 550
AYSENLQKIL NKSKSQESTG GPEEFTNINS VVIKPLDKNT LNCPPSFNIF
560 570 580 590 600
KQQQHSQAAQ SQSISAVGSG AGTPVTFTMA SGNASDLATT STVSVSAGTI
610 620 630 640 650
CINSPMMGTR PIISIQNKNI SLVLSKTTMA QQKPKMITTT TLSSQAALQM
660 670 680 690 700
HHALIQDSSA DKAGSSANSG SATSGASMQL KLTTANTPTK LSVSLAPDVV
710 720 730 740 750
KLEEVGSESK AKLLVKQEAV VKDSTGTPTS EERAEEIGTP EKRLNANATM
760 770 780 790 800
TAINQVQNQS ANQIQMATST STASNPSTPN PTVNATPMNN QRSAAEDNAL
810 820 830 840 850
LKQLLQNNSS SHSLNQISIT SAHVGSASAS APLSARKVIN VRAPSMGKVR
860 870 880 890 900
SLEDQLARPV IPPVPTATQA AGSSSSSGSV ATSTTTTTVA SGGSSQQVAT
910 920 930 940 950
ASATALPVSA VAITTPGVGG EAKLEQKSDQ PAAIMQNQSQ NQAPPPPPPP
960 970 980 990 1000
QQQQQQQLHQ PQQLQPSPHQ VKQTVQIVSK ETSFISGPVA AKTLVTEATS
1010 1020 1030 1040 1050
KPAELLPPPP YEMATAPISN VTISISTKQA APKELQMKPK AVAMSLPMEQ
1060 1070 1080 1090 1100
GDESLPEQAE PPLHSEQGAT AAGVAPHSGG PLVSAQWTNN HLEGGVATTK
1110 1120 1130 1140 1150
IPFKPGEPQK RKLPMHPQLD EKQIQQQAEI PISTSLPTTP TGQGTPDKVQ
1160 1170 1180 1190 1200
LISAIATYVK KSGVPNEAQP IQNQSQGQVQ MQAQMQATMQ GHLSGQMSGQ
1210 1220 1230 1240 1250
ISGHAAGQIP AQMHLQVQHQ LHMAVHPQQQ QQQLHQNQPQ NATIPLPVTG
1260 1270 1280 1290 1300
QGAVPIPVPT MESKAGDQRK RRKREVQKPR RTNLNAGQAG GALKDLTGPL
1310 1320 1330 1340 1350
PAGAMVQLAG MPPGTQYIQG AASGTGHVIT STGQGVTLGG VGASTGASSS
1360 1370 1380 1390 1400
PMLKKRVRKF SKVEEDHDAF TEKLLTHIRQ MQPLQVLEPH LNRNFHFLIG
1410 1420 1430 1440 1450
SNETSGGGSP ASMSSAASAG SSSAGGGKLK GGSRGWPLSR HLEGLEDCDG
1460 1470 1480 1490 1500
TVLGRYGRVN LPGIPSLYDS ERFGGSRGLV GGSARTRSPS PAESPGAEKM
1510 1520 1530 1540 1550
LPMSSIQNDF YDQEFSTHME RNPRERLVRH IGAVKDCNLE TVDLVESEGV
1560 1570 1580 1590 1600
AAWATLPRLT RYPGLILLNG NSRCHGRMSP VALPEDPLTM RFPVSPLLRS
1610 1620 1630 1640 1650
CGEELRKTQQ MELGMGPLGN NNNNNYQQKN QNVILALPAS ASENIAGVLR
1660 1670 1680 1690 1700
DLANLLHLAP ALTCKIIEDK IGNKLEDQFM NQDDEKHVDF KRPLSQVSHG
1710 1720 1730 1740 1750
HLRKILNGRR KLCRSCGNVV HATGLRVPRH SVPALEEQLP RLAQLMDMLP
1760 1770 1780 1790 1800
RKSVPPPFVY FCDRACFARF KWNGKDGQAE AASLLLQPAG GSAVKSSNGD
1810 1820 1830 1840 1850
SPGSFCASST APAEMVVKQE PEDEDEKTPS VPGNPTNIPA QRKCIVKCFS
1860 1870 1880 1890 1900
ADCFTTDSAP SGLELDGTAG AGTGAGPVNN TVWETETSGL QLEDTRQCVF
1910 1920 1930 1940 1950
CNQRGDGQAD GPSRLLNFDV DKWVHLNCAL WSNGVYETVS GALMNFQTAL
1960 1970 1980 1990 2000
QAGLSQACSA CHQPGATIKC FKSRCNSLYH LPCAIREECV FYKNKSVHCS
2010 2020 2030 2040 2050
VHGHAHAGIT MGAGAGATTG AGLGGSVADN ELSSLVVHRR VFVDRDENRQ
2060 2070 2080 2090 2100
VATVMHYSEL SNLLRVGNMT FLNVGQLLPH QLEAFHTPHY IYPIGYKVSR
2110 2120 2130 2140 2150
YYWCVRRPNR RCRYICSIAE AGCKPEFRIQ VQDAGDKEPE REFRGSSPSA
2160 2170 2180 2190 2200
VWQQILQPIT RLRKVHKWLQ LFPQHISGED LFGLTEPAIV RILESLPGIE
2210 2220 2230 2240 2250
TLTDYRFKYG RNPLLEFPLA INPSGAARTE PKQRQLLVWR KPHTQRTAGS
2260 2270 2280 2290 2300
CSTQRMANSA AIAGEVACPY SKQFVHSKSS QYKKMKQEWR NNVYLARSKI
2310 2320 2330 2340 2350
QGLGLYAARD IEKHTMIIEY IGEVIRTEVS EIREKQYESK NRGIYMFRLD
2360 2370 2380 2390 2400
EDRVVDATLS GGLARYINHS CNPNCVTEIV EVDRDVRIII FAKRKIYRGE
2410 2420 2430
ELSYDYKFDI EDESHKIPCA CGAPNCRKWM N
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