Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

BLAST

About BLAST

<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)Q8K4G1[672 - 713]
Description
Feature keyDomain
Feature identifier
        10         20         30         40         50
MRRPGLGGPC PLLLLLLLPA ATSASGSSPS PSPSPIEKAV VPSHQAGVAA 
        60         70         80         90        100
CHCCLDQTPK SSRCTRASCR VRNCPPAKCT GLEGCLTPTP SVPSPSRSPV 
       110        120        130        140        150
EKSQVSLNWQ PLTLQEARAL LRQRRPRGPW ARALLKRRPP HRAPAGQARV 
       160        170        180        190        200
LCPLICHNGG VCVKPDRCLC PPDFAGKFCQ LHSSGARPPA PAMPGLTRSV 
       210        220        230        240        250
YTMPLANHRD DEHGVASMVS VHVEHPQEAS VVVHQVERVS GPWEEANPEA 
       260        270        280        290        300
LARAEAAARA EAAAPYTVLA QSAPREDGYS DASGFGYCFR ELRGSECASP 
       310        320        330        340        350
LPGLRTQEVC CRGEGLAWGV HDCHPCAEHL RNSNQVSGPN GPCPPGFERV 
       360        370        380        390        400
NGSCVDVDEC ATGGRCQHGE CANTRGGYTC VCPDGFLLDS SRSSCISQHV 
       410        420        430        440        450
ISEAKGPCYR VLHDGGCSLP ILRNITKQIC CCSRVGKAWG RGCQLCPPYG 
       460        470        480        490        500
SEGFREICPA GPGYHYSASD LRYNTRPLNQ DPPRVTFNQP RVPPATPRPP 
       510        520        530        540        550
TGFLPTRRPE PRPDPGPQPE PRPRPEPRPR PESRPRPEPR PRPEPRPQPE 
       560        570        580        590        600
SQPRPESRPR PESQPWPEFP LPSIPAWTGP EIPESGPSSS MCQRNPQVCG 
       610        620        630        640        650
PGRCVPRPSG YTCACDPGFR LGPQGTRCID IDECRRVPTP CAPGRCENTP 
       660        670        680        690        700
GSFRCVCGTG FQAGPRATEC LDVDECRRVP PPCDRGRCEN TPGSFLCVCP 
       710        720        730        740        750
AGYQAAPHGA SCQDVDECTQ SPGLCGRGVC ENLPGSFRCV CPAGFRGSAC 
       760        770        780        790        800
EEDVDECAQQ PPPCGPGRCD NTAGSFHCAC PAGFRSRGPG APCQDVDECS 
       810        820        830        840        850
RSPSPCAYGR CENTEGSFKC VCPTGFQPNA AGSECEDVDE CENRLACPGQ 
       860        870        880        890        900
ECVNSPGSFQ CRACPVGHHL HRGRCTDVDE CSSGTPCGLH GQCTNTKGSF 
       910        920        930        940        950
HCSCSTGYRA PSGQPGPCAD INECLEGDFC FPHGECLNTD GSFTCTCAPG 
       960        970        980        990       1000
YRPGPRGASC LDVDECSEED LCQSGICTNT DGSFECICPP GHRAGPDLAS 
      1010       1020       1030       1040       1050
CLDIDECRER GPALCGSQRC ENSPGSYRCV RDCDPGYHPG PEGTCDDIDE 
      1060       1070       1080       1090       1100
CREYGSAICG AQRCENTPGS YRCTPACDPG YQPTPGGGCQ DVDECRNRSF 
      1110       1120       1130       1140       1150
CGAHAMCQNL PGSFQCVCDQ GYEGARDGRH CVDVNECETL QGVCGSALCE 
      1160       1170       1180       1190       1200
NVEGSFLCVC PNSPEEFDPM TGRCVPPRAP AGTFPGSQPQ APASPSLPAR 
      1210       1220       1230       1240       1250
PPAPPPPRRP SPPRQGPVSS GRRECYFDTA APDACDNILA RNVTWQECCC 
      1260       1270       1280       1290       1300
TVGEGWGSGC RIQQCPGTET AEYQSLCPHG RGYLVPSGDL SARRDVDECQ 
      1310       1320       1330       1340       1350
LFQDQVCKSG VCVNTAPGYS CYCSNGFYYH AHRLECVDND ECADEEPACE 
      1360       1370       1380       1390       1400
GGRCVNTVGS YHCTCEPPLV LDGSRRRCVS NESQSLDDNL GVCWQEVGPD 
      1410       1420       1430       1440       1450
LVCSRPRLDR QATYTECCCL YGEAWGMDCA LCPAQDSDDF EALCNVLRPP 
      1460       1470       1480       1490       1500
AYGPPRPGGF GIPYEYGPDI GPPYQSLPYG PDLYPPPVLP YDPYPPPPGP 
      1510       1520       1530       1540       1550
FARREAPYGA PPFDMPDFED DGGPYGESET PDPPSRGTGW PYRSRDTRGS 
      1560       1570       1580       1590       1600
FPEPEESSER GSYTGALSEP YEGLEAEECG ILDGCPHGRC VRVPEGFTCD 
      1610       1620       1630       1640       1650
CFDGYRLDIT RMSCVDVNEC DEAEATSPLC VNARCVNTDG SFRCICRPGF 
      1660 
APTHQPHHCA PARPRA
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again