Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)Q8K4G1[725 - 725, 739 - 739]
Description
Feature keyDisulfide bond
Feature identifier
        10         20         30         40         50
MRRPGLGGPC PLLLLLLLPA ATSASGSSPS PSPSPIEKAV VPSHQAGVAA
60 70 80 90 100
CHCCLDQTPK SSRCTRASCR VRNCPPAKCT GLEGCLTPTP SVPSPSRSPV
110 120 130 140 150
EKSQVSLNWQ PLTLQEARAL LRQRRPRGPW ARALLKRRPP HRAPAGQARV
160 170 180 190 200
LCPLICHNGG VCVKPDRCLC PPDFAGKFCQ LHSSGARPPA PAMPGLTRSV
210 220 230 240 250
YTMPLANHRD DEHGVASMVS VHVEHPQEAS VVVHQVERVS GPWEEANPEA
260 270 280 290 300
LARAEAAARA EAAAPYTVLA QSAPREDGYS DASGFGYCFR ELRGSECASP
310 320 330 340 350
LPGLRTQEVC CRGEGLAWGV HDCHPCAEHL RNSNQVSGPN GPCPPGFERV
360 370 380 390 400
NGSCVDVDEC ATGGRCQHGE CANTRGGYTC VCPDGFLLDS SRSSCISQHV
410 420 430 440 450
ISEAKGPCYR VLHDGGCSLP ILRNITKQIC CCSRVGKAWG RGCQLCPPYG
460 470 480 490 500
SEGFREICPA GPGYHYSASD LRYNTRPLNQ DPPRVTFNQP RVPPATPRPP
510 520 530 540 550
TGFLPTRRPE PRPDPGPQPE PRPRPEPRPR PESRPRPEPR PRPEPRPQPE
560 570 580 590 600
SQPRPESRPR PESQPWPEFP LPSIPAWTGP EIPESGPSSS MCQRNPQVCG
610 620 630 640 650
PGRCVPRPSG YTCACDPGFR LGPQGTRCID IDECRRVPTP CAPGRCENTP
660 670 680 690 700
GSFRCVCGTG FQAGPRATEC LDVDECRRVP PPCDRGRCEN TPGSFLCVCP
710 720 730 740 750
AGYQAAPHGA SCQDVDECTQ SPGLCGRGVC ENLPGSFRCV CPAGFRGSAC
760 770 780 790 800
EEDVDECAQQ PPPCGPGRCD NTAGSFHCAC PAGFRSRGPG APCQDVDECS
810 820 830 840 850
RSPSPCAYGR CENTEGSFKC VCPTGFQPNA AGSECEDVDE CENRLACPGQ
860 870 880 890 900
ECVNSPGSFQ CRACPVGHHL HRGRCTDVDE CSSGTPCGLH GQCTNTKGSF
910 920 930 940 950
HCSCSTGYRA PSGQPGPCAD INECLEGDFC FPHGECLNTD GSFTCTCAPG
960 970 980 990 1000
YRPGPRGASC LDVDECSEED LCQSGICTNT DGSFECICPP GHRAGPDLAS
1010 1020 1030 1040 1050
CLDIDECRER GPALCGSQRC ENSPGSYRCV RDCDPGYHPG PEGTCDDIDE
1060 1070 1080 1090 1100
CREYGSAICG AQRCENTPGS YRCTPACDPG YQPTPGGGCQ DVDECRNRSF
1110 1120 1130 1140 1150
CGAHAMCQNL PGSFQCVCDQ GYEGARDGRH CVDVNECETL QGVCGSALCE
1160 1170 1180 1190 1200
NVEGSFLCVC PNSPEEFDPM TGRCVPPRAP AGTFPGSQPQ APASPSLPAR
1210 1220 1230 1240 1250
PPAPPPPRRP SPPRQGPVSS GRRECYFDTA APDACDNILA RNVTWQECCC
1260 1270 1280 1290 1300
TVGEGWGSGC RIQQCPGTET AEYQSLCPHG RGYLVPSGDL SARRDVDECQ
1310 1320 1330 1340 1350
LFQDQVCKSG VCVNTAPGYS CYCSNGFYYH AHRLECVDND ECADEEPACE
1360 1370 1380 1390 1400
GGRCVNTVGS YHCTCEPPLV LDGSRRRCVS NESQSLDDNL GVCWQEVGPD
1410 1420 1430 1440 1450
LVCSRPRLDR QATYTECCCL YGEAWGMDCA LCPAQDSDDF EALCNVLRPP
1460 1470 1480 1490 1500
AYGPPRPGGF GIPYEYGPDI GPPYQSLPYG PDLYPPPVLP YDPYPPPPGP
1510 1520 1530 1540 1550
FARREAPYGA PPFDMPDFED DGGPYGESET PDPPSRGTGW PYRSRDTRGS
1560 1570 1580 1590 1600
FPEPEESSER GSYTGALSEP YEGLEAEECG ILDGCPHGRC VRVPEGFTCD
1610 1620 1630 1640 1650
CFDGYRLDIT RMSCVDVNEC DEAEATSPLC VNARCVNTDG SFRCICRPGF
1660
APTHQPHHCA PARPRA
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again