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BLAST

About BLAST

<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)Q92540[214 - 217]
Description
Feature keyBeta strand
Feature identifier
        10         20         30         40         50
MSLQSAQYLR QAEVLKADMT DSKLGPAEVW TSRQALQDLY QKMLVTDLEY 
        60         70         80         90        100
ALDKKVEQDL WNHAFKNQIT TLQGQAKNRA NPNRSEVQAN LSLFLEAASG 
       110        120        130        140        150
FYTQLLQELC TVFNVDLPCR VKSSQLGIIS NKQTHTSAIV KPQSSSCSYI 
       160        170        180        190        200
CQHCLVHLGD IARYRNQTSQ AESYYRHAAQ LVPSNGQPYN QLAILASSKG 
       210        220        230        240        250
DHLTTIFYYC RSIAVKFPFP AASTNLQKAL SKALESRDEV KTKWGVSDFI 
       260        270        280        290        300
KAFIKFHGHV YLSKSLEKLS PLREKLEEQF KRLLFQKAFN SQQLVHVTVI 
       310        320        330        340        350
NLFQLHHLRD FSNETEQHTY SQDEQLCWTQ LLALFMSFLG ILCKCPLQNE 
       360        370        380        390        400
SQEESYNAYP LPAVKVSMDW LRLRPRVFQE AVVDERQYIW PWLISLLNSF 
       410        420        430        440        450
HPHEEDLSSI SATPLPEEFE LQGFLALRPS FRNLDFSKGH QGITGDKEGQ 
       460        470        480        490        500
QRRIRQQRLI SIGKWIADNQ PRLIQCENEV GKLLFITEIP ELILEDPSEA 
       510        520        530        540        550
KENLILQETS VIESLAADGS PGLKSVLSTS RNLSNNCDTG EKPVVTFKEN 
       560        570        580        590        600
IKTREVNRDQ GRSFPPKEVR RDYSKGITVT KNDGKKDNNK RKTETKKCTL 
       610        620        630        640        650
EKLQETGKQN VAVQVKSQTE LRKTPVSEAR KTPVTQTPTQ ASNSQFIPIH 
       660        670        680        690        700
HPGAFPPLPS RPGFPPPTYV IPPPVAFSMG SGYTFPAGVS VPGTFLQPTA 
       710        720        730        740        750
HSPAGNQVQA GKQSHIPYSQ QRPSGPGPMN QGPQQSQPPS QQPLTSLPAQ 
       760        770        780        790        800
PTAQSTSQLQ VQALTQQQQS PTKAVPALGK SPPHHSGFQQ YQQADASKQL 
       810        820        830        840        850
WNPPQVQGPL GKIMPVKQPY YLQTQDPIKL FEPSLQPPVM QQQPLEKKMK 
       860        870        880        890        900
PFPMEPYNHN PSEVKVPEFY WDSSYSMADN RSVMAQQANI DRRGKRSPGV 
       910        920        930        940        950
FRPEQDPVPR MPFEKSLLEK PSELMSHSSS FLSLTGFSLN QERYPNNSMF 
       960        970        980        990       1000
NEVYGKNLTS SSKAELSPSM APQETSLYSL FEGTPWSPSL PASSDHSTPA 
      1010       1020       1030       1040       1050
SQSPHSSNPS SLPSSPPTHN HNSVPFSNFG PIGTPDNRDR RTADRWKTDK 
      1060       1070       1080       1090       1100
PAMGGFGIDY LSATSSSESS WHQASTPSGT WTGHGPSMED SSAVLMESLK 
      1110       1120       1130 
SIWSSSMMHP GPSALEQLLM QQKQKQQRGQ GTMNPPH
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