Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

<td id="blast-threshold">The expectation value (E) threshold is a statistical measure of the number of expected matches in a random database. The lower the e-value, the more likely the match is to be significant. E-values between 0.1 and 10 are generally dubious, and over 10 are unlikely to have biological significance. In all cases, those matches need to be verified manually. You may need to increase the E threshold if you have a very short query sequence, to detect very weak similarities, or similarities in a short region, or if your sequence has a low complexity region and you use the "filter" option</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>E-Thresholdi

<td id="blast-matrix">The matrix assigns a probability score for each position in an alignment. The BLOSUM matrix assigns a probability score for each position in an alignment that is based on the frequency with which that substitution is known to occur among consensus blocks within related proteins. BLOSUM62 is among the best of the available matrices for detecting weak protein similarities. The PAM set of matrices is also available. If "Auto" is set, the matrix will be selected depending on the query sequence length.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Matrixi

<td id="blast-filter">Low-complexity regions (e.g. stretches of cysteine in <a href="http://www.uniprot.org/uniprot/Q03751">Q03751</a>, or hydrophobic regions in membrane proteins) tend to produce spurious, insignificant matches with sequences in the database which have the same kind of low-complexity regions, but are unrelated biologically. If "Filter low complexity regions" is selected, the query sequence will be run through the program SEG, and all amino acids in low-complexity regions will be replaced by X's. </td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Filteringi

<td id="blast-gapped">This will allow gaps to be introduced in the sequences when the comparison is done.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Gappedi

<td id="blast-numal">Limits the number of returned alignments.</td><p><a href='/help/sequence-searches' target='_top'>More...</a></p>Hitsi

Sequence feature

Entry & position(s)Q92614-2
Description
Feature key
Feature identifier
        10         20         30         40         50
MRAKTEEQIA AEEAWNETEK VWLVHRDGFS LASQLKSEEL NLPEGKVRVK
60 70 80 90 100
LDHDGAILDV DEDDVEKANA PSCDRLEDLA SLVYLNESSV LHTLRQRYGA
110 120 130 140 150
SLLHTYAGPS LLVLGPRGAP AVYSEKVMHM FKGCRREDMA PHIYAVAQTA
160 170 180 190 200
YRAMLMSRQD QSIILLGSSG SGKTTSCQHL VQYLATIAGI SGNKVFSVEK
210 220 230 240 250
WQALYTLLEA FGNSPTIING NATRFSQILS LDFDQAGQVA SASIQTMLLE
260 270 280 290 300
KLRVARRPAS EATFNVFYYL LACGDGTLRT ELHLNHLAEN NVFGIVPLAK
310 320 330 340 350
PEEKQKAAQQ FSKLQAAMKV LGISPDEQKA CWFILAAIYH LGAAGATKEA
360 370 380 390 400
AEAGRKQFAR HEWAQKAAYL LGCSLEELSS AIFKHQHKGG TLQRSTSFRQ
410 420 430 440 450
GPEESGLGDG TGPKLSALEC LEGMAAGLYS ELFTLLVSLV NRALKSSQHS
460 470 480 490 500
LCSMMIVDTP GFQNPEQGGS ARGASFEELC HNYTQDRLQR LFHERTFVQE
510 520 530 540 550
LERYKEENIE LAFDDLEPPT DDSVAAVDQA SHQSLVRSLA RTDEARGLLW
560 570 580 590 600
LLEEEALVPG ASEDTLLERL FSYYGPQEGD KKGQSPLLHS SKPHHFLLGH
610 620 630 640 650
SHGTNWVEYN VTGWLNYTKQ NPATQNAPRL LQDSQKKIIS NLFLGRAGSA
660 670 680 690 700
TVLSGSIAGL EGGSQLALRR ATSMRKTFTT GMAAVKKKSL CIQMKLQVDA
710 720 730 740 750
LIDTIKKSKL HFVHCFLPVA EGWAGEPRSA SSRRVSSSSE LDLPSGDHCE
760 770 780 790 800
AGLLQLDVPL LRTQLRGSRL LDAMRMYRQG YPDHMVFSEF RRRFDVLAPH
810 820 830 840 850
LTKKHGRNYI VVDERRAVEE LLECLDLEKS SCCMGLSRVF FRAGTLARLE
860 870 880 890 900
EQRDEQTSRN LTLFQAACRG YLARQHFKKR KIQDLAIRCV QKNIKKNKGV
910 920 930 940 950
KDWPWWKLFT TVRPLIEVQL SEEQIRNKDE EIQQLRSKLE KAEKERNELR
960 970 980 990 1000
LNSDRLESRI SELTSELTDE RNTGESASQL LDAETAERLR AEKEMKELQT
1010 1020 1030 1040 1050
QYDALKKQME VMEMEVMEAR LIRAAEINGE VDDDDAGGEW RLKYERAVRE
1060 1070 1080 1090 1100
VDFTKKRLQQ EFEDKLEVEQ QNKRQLERRL GDLQADSEES QRALQQLKKK
1110 1120 1130 1140 1150
CQRLTAELQD TKLHLEGQQV RNHELEKKQR RFDSELSQAH EEAQREKLQR
1160 1170 1180 1190 1200
EKLQREKDML LAEAFSLKQQ LEEKDMDIAG FTQKVVSLEA ELQDISSQES
1210 1220 1230 1240 1250
KDEASLAKVK KQLRDLEAKV KDQEEELDEQ AGTIQMLEQA KLRLEMEMER
1260 1270 1280 1290 1300
MRQTHSKEME SRDEEVEEAR QSCQKKLKQM EVQLEEEYED KQKVLREKRE
1310 1320 1330 1340 1350
LEGKLATLSD QVNRRDFESE KRLRKDLKRT KALLADAQLM LDHLKNSAPS
1360 1370 1380 1390 1400
KREIAQLKNQ LEESEFTCAA AVKARKAMEV EIEDLHLQID DIAKAKTALE
1410 1420 1430 1440 1450
EQLSRLQREK NEIQNRLEED QEDMNELMKK HKAAVAQASR DLAQINDLQA
1460 1470 1480 1490 1500
QLEEANKEKQ ELQEKLQALQ SQVEFLEQSM VDKSLVSRQE AKIRELETRL
1510 1520 1530 1540 1550
EFERTQVKRL ESLASRLKEN MEKLTEERDQ RIAAENREKE QNKRLQRQLR
1560 1570 1580 1590 1600
DTKEEMGELA RKEAEASRKK HELEMDLESL EAANQSLQAD LKLAFKRIGD
1610 1620 1630 1640 1650
LQAAIEDEME SDENEDLINS LQDMVTKYQK RKNKLEGDSD VDSELEDRVD
1660 1670 1680 1690 1700
GVKSWLSKNK GPSKAASDDG SLKSSSPTSY WKSLAPDRSD DEHDPLDNTS
1710 1720
RPRYSHSYLS DSDTEAKLTE TNA
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again