| http://purl.uniprot.org/citations/10023776 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10023776 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10023776 | http://www.w3.org/2000/01/rdf-schema#comment | "Signaling through the B cell receptor (BCR) is essential for B cell function and development. Despite the key role of Syk in BCR signaling, little is known about the mechanism by which Syk transmits downstream effectors. BLNK (B cell LiNKer protein), a substrate for Syk, is now shown to be essential in activating phospholipase C (PLC)gamma 2 and JNK. The BCR-induced PLC gamma 2 activation, but not the JNK activation, was restored by introduction of PLC gamma 2 membrane-associated form into BLNK-deficient B cells. As JNK activation requires both Rac1 and PLC gamma 2, our results suggest that BLNK regulates the Rac1-JNK pathway, in addition to modulating PLC gamma 2 localization."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80012-6"xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80012-6"xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Iwamatsu A."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Iwamatsu A."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Kurosaki M."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Kurosaki M."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Kurosaki T."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Kurosaki T."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Shibata M."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Shibata M."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Ronko I."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Ronko I."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Fu C."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Fu C."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Okawa K."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Okawa K."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Chan A.C."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Chan A.C."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Ishiai M."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Ishiai M."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Pappu R."xsd:string |
| http://purl.uniprot.org/citations/10023776 | http://purl.uniprot.org/core/author | "Pappu R."xsd:string |