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http://purl.uniprot.org/citations/10094305http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10094305http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10094305http://www.w3.org/2000/01/rdf-schema#comment"We have identified a novel splicing factor, Isy1p, through two-hybrid screens for interacting proteins involved in nuclear pre-mRNA splicing. Isy1p was tagged and demonstrated to be part of the splicing machinery, associated with spliceosomes throughout the splicing reactions. At least a portion of the Isy1 protein population is associated with snRNAs; low levels of U5 and U6 snRNAs are coimmunoprecipitated specifically with Isy1p. When the ISY1 gene was knocked out, no defect in vegetative growth was observed. Using a sensitive in vivo splicing assay, however, we observed lower splicing efficiency in the isy1 null mutant compared to wild-type, indicating that Isy1 p is important in the optimization of splicing."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.org/dc/terms/identifier"doi:10.1017/s1355838299981396"xsd:string
http://purl.uniprot.org/citations/10094305http://purl.org/dc/terms/identifier"doi:10.1017/s1355838299981396"xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Kupiec M."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Kupiec M."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Beggs J.D."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Beggs J.D."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Dix I."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Dix I."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Russell C.S."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Russell C.S."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Yehuda S.B."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/author"Yehuda S.B."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/name"RNA"xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/name"RNA"xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/pages"360-368"xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/pages"360-368"xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/title"The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/title"The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae."xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/volume"5"xsd:string
http://purl.uniprot.org/citations/10094305http://purl.uniprot.org/core/volume"5"xsd:string