http://purl.uniprot.org/citations/10213692 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10213692 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10213692 | http://www.w3.org/2000/01/rdf-schema#comment | "Control of cyclin levels is critical for proper cell cycle regulation. In yeast, the stability of the G1 cyclin Cln1 is controlled by phosphorylation-dependent ubiquitination. Here it is shown that this reaction can be reconstituted in vitro with an SCF E3 ubiquitin ligase complex. Phosphorylated Cln1 was ubiquitinated by SCF (Skp1-Cdc53-F-box protein) complexes containing the F-box protein Grr1, Rbx1, and the E2 Cdc34. Rbx1 promotes association of Cdc34 with Cdc53 and stimulates Cdc34 auto-ubiquitination in the context of Cdc53 or SCF complexes. Rbx1, which is also a component of the von Hippel-Lindau tumor suppressor complex, may define a previously unrecognized class of E3-associated proteins."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.284.5414.662"xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.284.5414.662"xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Elledge S.J."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Elledge S.J."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Conaway J.W."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Conaway J.W."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Conaway R.C."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Conaway R.C."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Harper J.W."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Harper J.W."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Koepp D.M."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Koepp D.M."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Conrad M.N."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Conrad M.N."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Kamura T."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Kamura T."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Skowyra D."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/author | "Skowyra D."xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/10213692 | http://purl.uniprot.org/core/name | "Science"xsd:string |