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http://purl.uniprot.org/citations/10403562http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10403562http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10403562http://www.w3.org/2000/01/rdf-schema#comment"Screening for differentially expressed genes in cancer cell lines by the RNA differential display (DD) technique identified a novel mRNA that encodes a 26-kDa protein and is up-regulated in MCF-7 and BT-20 breast cancer cells. The predicted amino acid sequence showed 38% homology to Caenorhabditis elegans T12A2.7 protein, indicating that this is a possible human homologue for C. elegans T12A2.7 protein. The mRNA, designated DAM1 (DNA amplified in mammary carcinoma), was mapped at the 1p13.3-21 region, which is frequently altered in human breast cancer. By Southern blot analysis, we confirmed that the up-regulation of this novel gene is associated with gene amplification in MCF-7 (10-fold) and BT-20 (5-fold) cells. Our findings suggest that the DAM1 gene is a novel gene up-regulated by amplification in human breast cancer cell lines."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.org/dc/terms/identifier"doi:10.1016/s0304-3835(99)00091-9"xsd:string
http://purl.uniprot.org/citations/10403562http://purl.org/dc/terms/identifier"doi:10.1016/s0304-3835(99)00091-9"xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Kikuchi K."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Kikuchi K."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Yamaguchi K."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Yamaguchi K."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Tsukada T."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Tsukada T."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Manabe T."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Manabe T."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Hanzawa H."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Hanzawa H."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Nagasaki K."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Nagasaki K."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Maass N."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/author"Maass N."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/name"Cancer Lett."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/name"Cancer Lett."xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/pages"219-226"xsd:string
http://purl.uniprot.org/citations/10403562http://purl.uniprot.org/core/pages"219-226"xsd:string