| http://purl.uniprot.org/citations/10501226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10501226 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10501226 | http://www.w3.org/2000/01/rdf-schema#comment | "Phosphorylation of the glutamate receptor is an important mechanism of synaptic plasticity. Here, we show that the C terminus of GluR2 of the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptor is phosphorylated by protein kinase C and that serine-880 is the major phosphorylation site. This phosphorylation also occurs in human embryonic kidney (HEK) cells by addition of 12-O-tetradecanoylphorbol 13-acetate. Our immunoprecipitation experiment revealed that the phosphorylation of serine-880 in GluR2 drastically reduced the affinity for glutamate receptor-interacting protein (GRIP), a synaptic PDZ domain-containing protein, in vitro and in HEK cells. This result suggests that modulation of serine-880 phosphorylation in GluR2 controls the clustering of AMPA receptors at excitatory synapses and consequently contributes to synaptic plasticity."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1471-4159.1999.731765.x"xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1471-4159.1999.731765.x"xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/author | "Hirai H."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/author | "Hirai H."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/author | "Matsuda S."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/author | "Matsuda S."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/author | "Mikawa S."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/author | "Mikawa S."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/name | "J. Neurochem."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/name | "J. Neurochem."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/pages | "1765-1768"xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/pages | "1765-1768"xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/title | "Phosphorylation of serine-880 in GluR2 by protein kinase C prevents its C terminus from binding with glutamate receptor-interacting protein."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/title | "Phosphorylation of serine-880 in GluR2 by protein kinase C prevents its C terminus from binding with glutamate receptor-interacting protein."xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/volume | "73"xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://purl.uniprot.org/core/volume | "73"xsd:string |
| http://purl.uniprot.org/citations/10501226 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10501226 |
| http://purl.uniprot.org/citations/10501226 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10501226 |
| http://purl.uniprot.org/citations/10501226 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10501226 |
| http://purl.uniprot.org/citations/10501226 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10501226 |