| http://purl.uniprot.org/citations/10581025 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10581025 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10581025 | http://www.w3.org/2000/01/rdf-schema#comment | "Telomeres are DNA-protein structures that cap linear chromosomes and are essential for maintaining genomic stability and cell phenotype. We identified a novel human telomere-associated protein, TIN2, by interaction cloning using the telomeric DNA-binding-protein TRF1 as a bait. TIN2 interacted with TRF1 in vitro and in cells, and co-localized with TRF1 in nuclei and metaphase chromosomes. A mutant TIN2 that lacks amino-terminal sequences effects elongated human telomeres in a telomerase-dependent manner. Our findings suggest that TRF1 is insufficient for control of telomere length in human cells, and that TIN2 is an essential mediator of TRF1 function."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.org/dc/terms/identifier | "doi:10.1038/70508"xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.org/dc/terms/identifier | "doi:10.1038/70508"xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/author | "Kim S.-H."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/author | "Kim S.-H."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/author | "Campisi J."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/author | "Campisi J."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/author | "Kaminker P."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/author | "Kaminker P."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/date | "1999"xsd:gYear |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/name | "Nat. Genet."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/name | "Nat. Genet."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/pages | "405-412"xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/pages | "405-412"xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/title | "TIN2, a new regulator of telomere length in human cells."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/title | "TIN2, a new regulator of telomere length in human cells."xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/10581025 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10581025 |
| http://purl.uniprot.org/citations/10581025 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10581025 |
| http://purl.uniprot.org/citations/10581025 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10581025 |
| http://purl.uniprot.org/citations/10581025 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10581025 |