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http://purl.uniprot.org/citations/10618500http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10618500http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10618500http://www.w3.org/2000/01/rdf-schema#comment"A yeast two-hybrid screen revealed that regulatory subunits (RII) of PKAII bind the Yotiao protein. Yotiao interacts with the NR1 subunit of the NMDA receptor. A purified C-terminal fragment of Yotiao binds PKAII, via an RII binding site constituted by amino acid residues 1452-1469, with a dissociation constant (K(d)) between 50 and 90 nM in vitro. A stable complex composed of Yotiao, RII and NR1 was immunoprecipitated from whole rat brain extracts. Immunostaining analysis disclosed that Yotiao, RIIbeta and NR1 colocalize in striatal and cerebellar neurons. Co-assembly of Yotiao/PKAII complexes with NR1 subunits may promote cAMP-dependent modulation of NMDA receptor activity at synapses, thereby influencing brain development and synaptic plasticity."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.org/dc/terms/identifier"doi:10.1016/S0014-5793(99)01585-9"xsd:string
http://purl.uniprot.org/citations/10618500http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(99)01585-9"xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Gottesman M.E."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Gottesman M.E."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Rubin C.S."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Rubin C.S."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Avvedimento E.V."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Avvedimento E.V."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Feliciello A."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Feliciello A."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Cardone L."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Cardone L."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Varrone S."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Varrone S."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Garbi C."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Garbi C."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Ginsberg M.D."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/author"Ginsberg M.D."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/date"1999"xsd:gYear
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/10618500http://purl.uniprot.org/core/name"FEBS Lett"xsd:string