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http://purl.uniprot.org/citations/10675560http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10675560http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10675560http://www.w3.org/2000/01/rdf-schema#comment"In this work we report that the Saccharomyces cerevisiae RAD9, RAD24, RAD17, MEC1, MEC3 and RAD53 checkpoint genes are required for efficient non-homologous end joining (NHEJ). RAD9 and RAD24 function additionally in this process. Defective NHEJ in rad9Delta-rad24Delta, but not yku80Delta cells, is only partially rescued by imposing G1 or G2/M delays. Thus, checkpoint functions other than transient cell cycle delays may be required for normal levels of NHEJ. Epistasis analysis also indicated that YKU80 and RAD9/RAD24 function in the same pathway for repair of lesions caused by MMS and gamma-irradiation. Unlike NHEJ, the checkpoint pathway is not required for efficient site-specific integration of plasmid DNA into the yeast genome, which is RAD52-dependent, but RAD51-independent."xsd:string
http://purl.uniprot.org/citations/10675560http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(00)01180-7"xsd:string
http://purl.uniprot.org/citations/10675560http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(00)01180-7"xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/author"Lowndes N.F."xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/author"Lowndes N.F."xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/author"de la Torre-Ruiz M."xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/author"de la Torre-Ruiz M."xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/pages"311-315"xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/pages"311-315"xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/title"The Saccharomyces cerevisiae DNA damage checkpoint is required for efficient repair of double strand breaks by non-homologous end joining."xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/title"The Saccharomyces cerevisiae DNA damage checkpoint is required for efficient repair of double strand breaks by non-homologous end joining."xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/volume"467"xsd:string
http://purl.uniprot.org/citations/10675560http://purl.uniprot.org/core/volume"467"xsd:string
http://purl.uniprot.org/citations/10675560http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10675560
http://purl.uniprot.org/citations/10675560http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10675560
http://purl.uniprot.org/citations/10675560http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10675560
http://purl.uniprot.org/citations/10675560http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10675560
http://purl.uniprot.org/uniprot/P32807http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/10675560
http://purl.uniprot.org/uniprot/Q04437http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/10675560