http://purl.uniprot.org/citations/10733938 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10733938 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10733938 | http://www.w3.org/2000/01/rdf-schema#comment | "To find a possible signal interacting with the Jak3 N-terminal, we screened the human peripheral blood cDNA library through both a two-hybrid system and a tyrosine-phosphorylation-modified two-hybrid system using the N-terminal of Jak3 as bait. Results showed that one new homologue of myosin heavy chain, designated MAJN (molecule associated with Jak3 N-terminal), could bind to Jak3 in a tyrosine-phosphorylation-independent manner. The interaction between Jak3 and MAJN was further confirmed by immunoprecipitation in BAF-B03 beta cells. To investigate the function of MAJN, we have constructed the BAF-B03 beta/MAJN cell line that stably expresses MAJN and found that overexpression of MAJN can partially inhibit the apoptosis induced by interleukin-2 deprival. Further studies are needed to elucidate how MAJN executes its function to antagonize BAF-B03beta cell death in the absence of IL-2."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2000.2413"xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2000.2413"xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Liu X."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Liu X."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Sun L."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Sun L."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Zhu J."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Zhu J."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Zheng Z."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Zheng Z."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Zhai Q."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Zhai Q."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Yan M."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Yan M."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Ji H."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/author | "Ji H."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/pages | "267-271"xsd:string |
http://purl.uniprot.org/citations/10733938 | http://purl.uniprot.org/core/pages | "267-271"xsd:string |