http://purl.uniprot.org/citations/10749931 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10749931 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/10749931 | http://www.w3.org/2000/01/rdf-schema#comment | "This work describes BRN1, the budding yeast homologue of Drosophila Barren and Xenopus condensin subunit XCAP-H. The Drosophila protein is required for proper chromosome segregation in mitosis, and Xenopus protein functions in mitotic chromosome condensation. Mutant brn1 cells show a defect in mitotic chromosome condensation and sister chromatid separation and segregation in anaphase. Chromatid cohesion before anaphase is properly maintained in the mutants. Some brn1 mutant cells apparently arrest in S-phase, pointing to a possible function for Brn1p at this stage of the cell cycle. Brn1p is a nuclear protein with a nonuniform distribution pattern, and its level is up-regulated at mitosis. Temperature-sensitive mutations of BRN1 can be suppressed by overexpression of a novel gene YCG1, which is homologous to another Xenopus condensin subunit, XCAP-G. Overexpression of SMC2, a gene necessary for chromosome condensation, and a homologue of the XCAP-E condensin, does not suppress brn1, pointing to functional specialization of components of the condensin complex."xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.11.4.1305"xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.11.4.1305"xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/author | "Brinkley B.R."xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/author | "Brinkley B.R."xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/author | "Ouspenski I.I."xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/author | "Ouspenski I.I."xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/author | "Cabello O.A."xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/author | "Cabello O.A."xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/pages | "1305-1313"xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/pages | "1305-1313"xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/title | "Chromosome condensation factor Brn1p is required for chromatid separation in mitosis."xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/title | "Chromosome condensation factor Brn1p is required for chromatid separation in mitosis."xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/volume | "11"xsd:string |
http://purl.uniprot.org/citations/10749931 | http://purl.uniprot.org/core/volume | "11"xsd:string |
http://purl.uniprot.org/citations/10749931 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10749931 |
http://purl.uniprot.org/citations/10749931 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10749931 |
http://purl.uniprot.org/citations/10749931 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10749931 |
http://purl.uniprot.org/citations/10749931 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10749931 |