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http://purl.uniprot.org/citations/10749931http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10749931http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10749931http://www.w3.org/2000/01/rdf-schema#comment"This work describes BRN1, the budding yeast homologue of Drosophila Barren and Xenopus condensin subunit XCAP-H. The Drosophila protein is required for proper chromosome segregation in mitosis, and Xenopus protein functions in mitotic chromosome condensation. Mutant brn1 cells show a defect in mitotic chromosome condensation and sister chromatid separation and segregation in anaphase. Chromatid cohesion before anaphase is properly maintained in the mutants. Some brn1 mutant cells apparently arrest in S-phase, pointing to a possible function for Brn1p at this stage of the cell cycle. Brn1p is a nuclear protein with a nonuniform distribution pattern, and its level is up-regulated at mitosis. Temperature-sensitive mutations of BRN1 can be suppressed by overexpression of a novel gene YCG1, which is homologous to another Xenopus condensin subunit, XCAP-G. Overexpression of SMC2, a gene necessary for chromosome condensation, and a homologue of the XCAP-E condensin, does not suppress brn1, pointing to functional specialization of components of the condensin complex."xsd:string
http://purl.uniprot.org/citations/10749931http://purl.org/dc/terms/identifier"doi:10.1091/mbc.11.4.1305"xsd:string
http://purl.uniprot.org/citations/10749931http://purl.org/dc/terms/identifier"doi:10.1091/mbc.11.4.1305"xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/author"Brinkley B.R."xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/author"Brinkley B.R."xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/author"Ouspenski I.I."xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/author"Ouspenski I.I."xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/author"Cabello O.A."xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/author"Cabello O.A."xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/name"Mol. Biol. Cell"xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/name"Mol. Biol. Cell"xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/pages"1305-1313"xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/pages"1305-1313"xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/title"Chromosome condensation factor Brn1p is required for chromatid separation in mitosis."xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/title"Chromosome condensation factor Brn1p is required for chromatid separation in mitosis."xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/volume"11"xsd:string
http://purl.uniprot.org/citations/10749931http://purl.uniprot.org/core/volume"11"xsd:string
http://purl.uniprot.org/citations/10749931http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10749931
http://purl.uniprot.org/citations/10749931http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10749931
http://purl.uniprot.org/citations/10749931http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10749931
http://purl.uniprot.org/citations/10749931http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10749931