| http://purl.uniprot.org/citations/10760246 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10760246 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10760246 | http://www.w3.org/2000/01/rdf-schema#comment | "Profilin is an actin monomer binding protein that, depending on the conditions, causes either polymerization or depolymerization of actin filaments. In plants, profilins are encoded by multigene families. In this study, an analysis of native and recombinant proteins from maize demonstrates the existence of two classes of functionally distinct profilin isoforms. Class II profilins, including native endosperm profilin and a new recombinant protein, ZmPRO5, have biochemical properties that differ from those of class I profilins. Class II profilins had higher affinity for poly-l-proline and sequestered more monomeric actin than did class I profilins. Conversely, a class I profilin inhibited hydrolysis of membrane phosphatidylinositol-4,5-bisphosphate by phospholipase C more strongly than did a class II profilin. These biochemical properties correlated with the ability of class II profilins to disrupt actin cytoplasmic architecture in live cells more rapidly than did class I profilins. The actin-sequestering activity of both maize profilin classes was found to be dependent on the concentration of free calcium. We propose a model in which profilin alters cellular concentrations of actin polymers in response to fluctuations in cytosolic calcium concentration. These results provide strong evidence that the maize profilin gene family consists of at least two classes, with distinct biochemical and live-cell properties, implying that the maize profilin isoforms perform distinct functions in the plant."xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.org/dc/terms/identifier | "doi:10.1105/tpc.12.4.583"xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.org/dc/terms/identifier | "doi:10.1105/tpc.12.4.583"xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/author | "Staiger C.J."xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/author | "Staiger C.J."xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/author | "Kovar D.R."xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/author | "Kovar D.R."xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/author | "Droebak B.K."xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/author | "Droebak B.K."xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/name | "Plant Cell"xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/name | "Plant Cell"xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/pages | "583-598"xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/pages | "583-598"xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/title | "Maize profilin isoforms are functionally distinct."xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/title | "Maize profilin isoforms are functionally distinct."xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/10760246 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10760246 |
| http://purl.uniprot.org/citations/10760246 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/10760246 |
| http://purl.uniprot.org/citations/10760246 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10760246 |
| http://purl.uniprot.org/citations/10760246 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/10760246 |