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http://purl.uniprot.org/citations/10783163http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10783163http://www.w3.org/2000/01/rdf-schema#comment"Werner syndrome (WS) is the hallmark premature aging disorder in which affected humans appear older than their chronological age. The protein WRNp, defective in WS, has helicase function, DNA-dependent ATPase, and exonuclease activity. Although WRNp functions in nucleic acid metabolism, there is little or no information about the pathways or protein interactions in which it participates. Here we identify Ku70 and Ku86 as proteins that interact with WRNp. Although Ku proteins had no effect on ATPase or helicase activity, they strongly stimulated specific exonuclease activity. These results suggest that WRNp and the Ku complex participate in a common DNA metabolic pathway."xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/author"Bohr V.A."xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/author"Cooper M.P."xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/author"Orren D.K."xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/author"Ramsden D."xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/author"Machwe A."xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/author"Brosh R.M."xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/name"Genes Dev"xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/pages"907-912"xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/title"Ku complex interacts with and stimulates the Werner protein."xsd:string
http://purl.uniprot.org/citations/10783163http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/10783163http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10783163
http://purl.uniprot.org/citations/10783163http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10783163
http://purl.uniprot.org/uniprot/Q14191#attribution-DDEE9FBACA322B2C35AC3F6E69E72FAAhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/10783163
http://purl.uniprot.org/uniprot/#_Q14191-mappedCitation-10783163http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10783163
http://purl.uniprot.org/uniprot/#_P12956-mappedCitation-10783163http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10783163
http://purl.uniprot.org/uniprot/#_P13010-mappedCitation-10783163http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/10783163
http://purl.uniprot.org/uniprot/P12956http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/10783163
http://purl.uniprot.org/uniprot/Q14191http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/10783163
http://purl.uniprot.org/uniprot/P13010http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/10783163