| http://purl.uniprot.org/citations/10873669 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10873669 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/10873669 | http://www.w3.org/2000/01/rdf-schema#comment | "Cadherin is a well-known cell-cell adhesion molecule, and it binds to beta-catenin, which in turn binds to alpha-catenin. However, little is known about the regulatory mechanism underlying the cadherin-mediated cell-cell adhesion. Here we purified two novel beta-catenin-interacting proteins with molecular masses of 180 kDa (p180) and 150 kDa (p150) from bovine brain cytosol by using glutathione S-transferase (GST)-beta-catenin affinity column chromatography. Mass spectral analysis revealed p180 to be identical to KIAA0313 which has a putative Rap1 guanine nucleotide exchange factor (GEF) domain and p150 to be the same as KIAA0705 which has a high degree of sequence similarity to the synaptic scaffolding molecule (S-SCAM), which binds beta-catenin and KIAA0313 in the yeast two-hybrid system and overlay assay, respectively (Ide et al., Biochem. Biophys. Res. Commun. 256, 456-461, 1999; Ohtsuka et al., Biochem. Biophys. Res. Commun. 265, 38-44, 1999). beta-Catenin was coimmunoprecipitated with KIAA0313 in Madin-Darby canine kidney II (MDCKII) cells, bovine brain cytosol, and EL cells. KIAA0313 and beta-catenin were partly colocalized at sites of cell-cell contact in MDCKII cells. Taken together, our data suggest that KIAA0313 associates with beta-catenin through KIAA0705 in vivo at sites of cell-cell contact."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2000.3002"xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2000.3002"xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Iwamatsu A."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Iwamatsu A."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Itoh N."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Itoh N."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Nakagawa M."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Nakagawa M."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Kaibuchi K."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Kaibuchi K."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Fukata M."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Fukata M."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Kawajiri A."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Kawajiri A."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Yamaga M."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/author | "Yamaga M."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/pages | "712-717"xsd:string |
| http://purl.uniprot.org/citations/10873669 | http://purl.uniprot.org/core/pages | "712-717"xsd:string |