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http://purl.uniprot.org/citations/10978503http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10978503http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/10978503http://www.w3.org/2000/01/rdf-schema#comment"Phosphoproteins or phosphophoryns (PPs) are the most abundant (>50%) non-collagenous proteins (NCPs) in dentin. PPs bind to calcium and hydroxyapatite and are believed to play a crucial role in dentin mineralization. Dentin sialoprotein (DSP), a highly glycosylated protein, comprised 5-8% of NCPs in dentin. The coding sequences for these two major NCPs are known to be contiguously located (i.e. DSP-PP) at the cDNA and genomic DNA levels in both rat and mouse. Previous studies have demonstrated the presence of multiple DSP-PP transcripts in the total RNA of adult rat incisors. To further understand the nature of these multiple transcripts, we performed reverse transcription-PCR and obtained a PP cDNA variant which encoded a 171 amino acid peptide (PP(171)) that shares many of the same characteristics as that of the published rat PP(240) sequence [Ritchie, H.H. and Wang, L.-H., J. Biol. Chem. 271 (1996) 21695-21698]. Due to its reduced size, as compared to PP(240), this cDNA encodes a phosphorylated protein with a reduced negative charge that may differentially affect mineralization processes. We provide evidence that there are multiple DSP-PP transcripts with various sizes of PP sequences in rat."xsd:string
http://purl.uniprot.org/citations/10978503http://purl.org/dc/terms/identifier"doi:10.1016/s0167-4781(00)00150-0"xsd:string
http://purl.uniprot.org/citations/10978503http://purl.org/dc/terms/identifier"doi:10.1016/s0167-4781(00)00150-0"xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/author"Wang L.-H."xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/author"Wang L.-H."xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/author"Ritchie H.H."xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/author"Ritchie H.H."xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/date"2000"xsd:gYear
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/name"Biochim. Biophys. Acta"xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/name"Biochim. Biophys. Acta"xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/pages"27-32"xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/pages"27-32"xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/title"The presence of multiple rat DSP-PP transcripts."xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/title"The presence of multiple rat DSP-PP transcripts."xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/volume"1493"xsd:string
http://purl.uniprot.org/citations/10978503http://purl.uniprot.org/core/volume"1493"xsd:string
http://purl.uniprot.org/citations/10978503http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10978503
http://purl.uniprot.org/citations/10978503http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/10978503
http://purl.uniprot.org/citations/10978503http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10978503
http://purl.uniprot.org/citations/10978503http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/10978503
http://purl.uniprot.org/uniprot/Q62598http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/10978503
http://purl.uniprot.org/uniprot/Q62598#attribution-D706DB61DBDD12B02C0485D9A95EE10Dhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/10978503