| http://purl.uniprot.org/citations/11130971 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11130971 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11130971 | http://www.w3.org/2000/01/rdf-schema#comment | "We have previously reported that CDV (carnitine deficiency-associated gene expressed in ventricle)-1 was a downregulated gene in the hypertrophied ventricle of carnitine-deficient juvenile visceral steatosis mice and that the related gene (CDV-1R) showed no tissue specificity and no sensitivity to carnitine deficiency. In the present paper, the CDV-1/1R gene was isolated from a mouse genomic BAC library, and the genomic structure was characterized. We found that the CDV-1/1R gene consisted of at least 19 exons and encompassed approximately 48 kb. The splice sites conformed to the GT-AG rule, and the CDV-1R mRNA containing 19 exons was processed. CDV-1 mRNA containing 5 exons was constructed from the 3' half of CDV-1R. The first exon of CDV-1 consisted of the 3' side (116 bp) of intron 14 and exon 15 (87 bp) of CDV-1R. The presumed promoter sequence for CDV-1 located in the intron 14 of CDV-1R contained the common TATA box and consensus binding sites for various transcription factors (Nkx-2.5, Spl, C/EBP, SRF, YY1, and CREB), which seem to play roles in the heart-specific expression and carnitine deficiency-associated suppression of CDV-1. In the upstream region of the CDV-1 promoter, we found two VNTRs, 13 repeats of GATA1, and 16 copies of STRE involved in yeast stress response. The CDV-1/1R gene was located close to DSMIT68 on mouse Chromosome (Chr) 5, corresponding to human Chr 12q24. All these data revealed that two mRNA species, CDV-1 and CDV-1R, are expressed tissue-specifically by using promoters peculiar to each transcript in a single gene."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.org/dc/terms/identifier | "doi:10.1007/s003350010207"xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.org/dc/terms/identifier | "doi:10.1007/s003350010207"xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Iijima M."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Iijima M."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Horiuchi M."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Horiuchi M."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Yasuda T."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Yasuda T."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Kobayashi K."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Kobayashi K."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Wakana S."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Wakana S."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Higashi M."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Higashi M."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Saheki T."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Saheki T."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Kanmura Y."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Kanmura Y."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Yoshida G."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/author | "Yoshida G."xsd:string |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/11130971 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |