http://purl.uniprot.org/citations/11337588 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11337588 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11337588 | http://www.w3.org/2000/01/rdf-schema#comment | "SCF ubiquitin ligases control various processes by marking regulatory proteins for ubiquitin-dependent proteolysis. To illuminate how SCF complexes are regulated, we sought proteins that interact with the human SCF component CUL1. The COP9 signalosome (CSN), a suppressor of plant photomorphogenesis, associated with multiple cullins and promoted cleavage of the ubiquitin-like protein NEDD8 from Schizosaccharomyces pombe CUL1 in vivo and in vitro. Multiple NEDD8-modified proteins uniquely accumulated in CSN-deficient S. pombe cells. We propose that the broad spectrum of activities previously attributed to CSN subunits--including repression of photomorphogenesis, activation of JUN, and activation of p27 nuclear export--underscores the importance of dynamic cycles of NEDD8 attachment and removal in biological regulation."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1059780"xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1059780"xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Zhou C."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Zhou C."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Tsuge T."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Tsuge T."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Shevchenko A."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Shevchenko A."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Wei N."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Wei N."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Shevchenko A.'"xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Shevchenko A.'"xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Serino G."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Serino G."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Deshaies R.J."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Deshaies R.J."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Wolf D.A."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Wolf D.A."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Lyapina S."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Lyapina S."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Cope G."xsd:string |
http://purl.uniprot.org/citations/11337588 | http://purl.uniprot.org/core/author | "Cope G."xsd:string |