http://purl.uniprot.org/citations/11387475 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11387475 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11387475 | http://www.w3.org/2000/01/rdf-schema#comment | "The delivery of soluble hydrolases to lysosomes is mediated by the cation-independent and cation-dependent mannose 6-phosphate receptors. The cytosolic tails of both receptors contain acidic-cluster-dileucine signals that direct sorting from the trans-Golgi network to the endosomal-lysosomal system. We found that these signals bind to the VHS domain of the Golgi-localized, gamma-ear-containing, ARF-binding proteins (GGAs). The receptors and the GGAs left the trans-Golgi network on the same tubulo-vesicular carriers. A dominant-negative GGA mutant blocked exit of the receptors from the trans-Golgi network. Thus, the GGAs appear to mediate sorting of the mannose 6-phosphate receptors at the trans-Golgi network."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1060750"xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1060750"xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Bonifacino J.S."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Bonifacino J.S."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Aguilar R.C."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Aguilar R.C."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Crouch R.J."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Crouch R.J."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Gorshkova I."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Gorshkova I."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Puertollano R."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/author | "Puertollano R."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/pages | "1712-1716"xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/pages | "1712-1716"xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/title | "Sorting of mannose 6-phosphate receptors mediated by the GGAs."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/title | "Sorting of mannose 6-phosphate receptors mediated by the GGAs."xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/volume | "292"xsd:string |
http://purl.uniprot.org/citations/11387475 | http://purl.uniprot.org/core/volume | "292"xsd:string |