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http://purl.uniprot.org/citations/11422376http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11422376http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11422376http://www.w3.org/2000/01/rdf-schema#comment"Mitochondrial chaperonins are necessary for the folding of newly imported and stress-denatured mitochondrial proteins. The goal of this study was to investigate the structure and function of the mammalian mitochondrial chaperonin system. We present evidence that the 60 kDa chaperonin (mt-cpn60) exists in solution in dynamic equilibrium between monomers, heptameric single rings and double-ringed tetradecamers. In the presence of ATP and the 10 kDa cochaperonin (mt-cpn10), the formation of a double ring is favored. ADP at very high concentrations does not inhibit malate dehydrogenase refolding or ATP hydrolysis by mt-cpn60 in the presence of mt-cpn10. We propose that the cis (mt-cpn60)14.nucleotide.(mt-cpn10)7 complex is not a stable species and does not bind ADP effectively at its trans binding site."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.org/dc/terms/identifier"doi:10.1046/j.1432-1327.2001.02243.x"xsd:string
http://purl.uniprot.org/citations/11422376http://purl.org/dc/terms/identifier"doi:10.1046/j.1432-1327.2001.02243.x"xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Lustig A."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Lustig A."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Weiss C."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Weiss C."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Azem A."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Azem A."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Niv A."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Niv A."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Sharkia R."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Sharkia R."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Greenberg A."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Greenberg A."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Delarea Y."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Delarea Y."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Levy-Rimler G."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Levy-Rimler G."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Viitanen P."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/author"Viitanen P."xsd:string
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11422376http://purl.uniprot.org/core/date"2001"xsd:gYear