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http://purl.uniprot.org/citations/11532455http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11532455http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11532455http://www.w3.org/2000/01/rdf-schema#comment"A refined structure of the human water channel aquaporin-1 is presented. The model rests on the high resolution X-ray structure of the homologous bacterial glycerol transporter GlpF, electron crystallographic data at 3.8 A resolution and a multiple sequence alignment of the aquaporin superfamily. The crystallographic R and free R values (36.7% and 37.8%) for the refined structure are significantly lower than for previous models. Improved geometry and enhanced stability in molecular dynamics simulations demonstrate a significant improvement of the aquaporin-1 structure. Comparison with previous aquaporin-1 models shows significant differences, not only in the loop regions, but also in the core of the water channel."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(01)02743-0"xsd:string
http://purl.uniprot.org/citations/11532455http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(01)02743-0"xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/author"Engel A."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/author"Engel A."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/author"de Groot B.L."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/author"de Groot B.L."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/author"Grubmueller H."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/author"Grubmueller H."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/pages"206-211"xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/pages"206-211"xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/title"A refined structure of human aquaporin-1."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/title"A refined structure of human aquaporin-1."xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/volume"504"xsd:string
http://purl.uniprot.org/citations/11532455http://purl.uniprot.org/core/volume"504"xsd:string
http://purl.uniprot.org/citations/11532455http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11532455
http://purl.uniprot.org/citations/11532455http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11532455
http://purl.uniprot.org/citations/11532455http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11532455
http://purl.uniprot.org/citations/11532455http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11532455