RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/11532953http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11532953http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11532953http://www.w3.org/2000/01/rdf-schema#comment"Transcription by RNA polymerase I on nucleosomal templates requires binding of the transcription termination factor TTF-I to a cognate site 160 bp upstream of the transcription start site. Binding of TTF-I is accompanied by changes in the chromatin architecture which suggests that TTF-I recruits a remodeling activity to the rDNA promoter. We have cloned a cDNA that encodes TIP5 (TTF-I-interacting protein 5), a 205 kDa protein that shares a number of important protein domains with WSTF (Williams syndrome transcription factor) and hAcf1/WCRF180, the largest subunits of human chromatin remodeling complexes hCHRAC and WCRF. TIP5 co-localizes with the basal RNA polymerase I transcription factor UBF in the nucleolus and is associated with SNF2h. The cellular TIP5-SNF2h complex, termed NoRC (nucleolar remodeling complex), induces nucleosome sliding in an ATP- and histone H4 tail-dependent fashion. The results suggest that NoRC is a novel nucleolar chromatin remodeling machine that may serve a role in the regulation of the rDNA locus."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.org/dc/terms/identifier"doi:10.1093/emboj/20.17.4892"xsd:string
http://purl.uniprot.org/citations/11532953http://purl.org/dc/terms/identifier"doi:10.1093/emboj/20.17.4892"xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Nemeth A."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Nemeth A."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Jansa P."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Jansa P."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Grummt I."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Grummt I."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Hofmann-Rohrer U."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Hofmann-Rohrer U."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Laengst G."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Laengst G."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Santoro R."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Santoro R."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Strohner R."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/author"Strohner R."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/name"EMBO J."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/name"EMBO J."xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/pages"4892-4900"xsd:string
http://purl.uniprot.org/citations/11532953http://purl.uniprot.org/core/pages"4892-4900"xsd:string