| http://purl.uniprot.org/citations/11684085 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11684085 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11684085 | http://www.w3.org/2000/01/rdf-schema#comment | "Phosphoprotein associated with GEMs (PAG), also known as Csk-binding protein (Cbp), is a broadly expressed palmitoylated transmembrane adapter protein found in membrane rafts, also called GEMs (glycosphingolipid-enriched membrane microdomains). PAG is known to bind and activate the essential regulator of Src-family kinases, cytoplasmic protein tyrosine kinase Csk. In the present study we used the yeast 2-hybrid system to search for additional proteins which might bind to PAG. We have identified the abundant cytoplasmic adapter protein EBP50 (ezrin/radixin/moesin (ERM)-binding phosphoprotein of 50 kDa), also known as NHERF (Na(+)/H(+) exchanger regulatory factor), as a specific PAG-binding partner. The interaction involves the C-terminal sequence (TRL) of PAG and N-terminal PDZ domain(s) of EBP50. As EBP50 is known to interact via its C-terminal domain with the ERM-family proteins, which in turn bind to actin cytoskeleton, the PAG-EBP50 interaction may be important for connecting membrane rafts to the actin cytoskeleton."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(01)02955-6"xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(01)02955-6"xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Milgram S.L."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Milgram S.L."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Andera L."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Andera L."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Angelisova P."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Angelisova P."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Brdicka T."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Brdicka T."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Horejsi V."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Horejsi V."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Brdickova N."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Brdickova N."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Spicka J."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/author | "Spicka J."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/pages | "133-136"xsd:string |
| http://purl.uniprot.org/citations/11684085 | http://purl.uniprot.org/core/pages | "133-136"xsd:string |