http://purl.uniprot.org/citations/11697142 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11697142 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11697142 | http://www.w3.org/2000/01/rdf-schema#comment | "Rapid, nongenomic effects of steroids are likely to be mediated by membrane receptors not by intracellular steroid receptors. We recently identified a progesterone membrane binding protein (mPR) from human liver. The corresponding hmpr gene is comprised of 3 exons and 2 introns. The promoter sequence of hmpr lacks a typical TATA box but contains instead a high homology to a transcription Initiatior consensus sequence, which overlaps the experimentally determined transcriptional start site. The major proximal promoter is GC-rich and sequence analysis revealed a CpG island spanning the transcriptional start site. Several putative cis-regulatory DNA-motifs, which represent possible binding sites for transcription factors like AP2, NF-AT, Ahr/Arnt and C/EBP were identified in the genomic upstream region by sequence homology. Functional analysis of differently deleted fragments of the hmpr upstream region in a GFP-reportergene assay in transiently transfected cultured cells indicates the general testability of the hmpr promoter in vivo."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.org/dc/terms/identifier | "doi:10.3109/10425170109042047"xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.org/dc/terms/identifier | "doi:10.3109/10425170109042047"xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/author | "Falkenstein E."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/author | "Falkenstein E."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/author | "Gerdes D."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/author | "Gerdes D."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/author | "Bernauer S."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/author | "Bernauer S."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/author | "Wehling M."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/author | "Wehling M."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/name | "DNA Seq."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/name | "DNA Seq."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/pages | "13-25"xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/pages | "13-25"xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/title | "The human membrane progesterone receptor gene: genomic structure and promoter analysis."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/title | "The human membrane progesterone receptor gene: genomic structure and promoter analysis."xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/volume | "12"xsd:string |
http://purl.uniprot.org/citations/11697142 | http://purl.uniprot.org/core/volume | "12"xsd:string |
http://purl.uniprot.org/citations/11697142 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11697142 |
http://purl.uniprot.org/citations/11697142 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11697142 |