http://purl.uniprot.org/citations/11860508 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11860508 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11860508 | http://www.w3.org/2000/01/rdf-schema#comment | "The treatment of Alzheimer's disease (AD) remains a major challenge because of the incomplete understanding of the triggering events that lead to the selective neurodegeneration characteristic of AD brains. Here we describe a new protein, CGI-94, that is down-regulated at the mRNA level in the hippocampus of early stage AD brain. Transfection experiments with CGI-94 as a green fluorescent protein (GFP)-fusion-protein show that this protein is translocated into the nucleus of the cell. The finding that this protein, which has a bipartite nuclear localization signal, is also observed in the cytoplasm and extracellular space points to a multifunctional protein. Immunohistochemical analyses reveal that CGI-94 is mainly expressed in neurons of the hippocampal formation and the cortex but not in the cerebellar nucleus. In conclusion, the expression of the nucleolar phosphoprotein CGI-94 appears to be disturbed in early processes of neuronal degeneration."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.0953-816x.2001.01836.x"xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.0953-816x.2001.01836.x"xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Li F."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Li F."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Nagai Y."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Nagai Y."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Nakayama T."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Nakayama T."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Yamamoto T."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Yamamoto T."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Kosaka K."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Kosaka K."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Heese K."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Heese K."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Sawada T."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Sawada T."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Akatsu H."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Akatsu H."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Hata R."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Hata R."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Suemoto T."xsd:string |
http://purl.uniprot.org/citations/11860508 | http://purl.uniprot.org/core/author | "Suemoto T."xsd:string |