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http://purl.uniprot.org/citations/11886743http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11886743http://www.w3.org/2000/01/rdf-schema#comment"Protein aggregation is involved in several human diseases, and presumed to be an important process in protein quality control. In bacteria, aggregation of proteins occurs during stress conditions, such as heat shock. We studied the protein aggregates of Escherichia coli during heat shock. Our results demonstrate that the concentration and diversity of proteins in the aggregates depend on the availability of proteases. Aggregates obtained from mutants in the Lon (La) protease contain three times more protein than wild-type aggregates and show the broadest protein diversity. The results support the assumption that protein aggregates are formed from partially unfolded proteins that were not refolded by chaperones or degraded by proteases."xsd:string
http://purl.uniprot.org/citations/11886743http://purl.org/dc/terms/identifier"doi:10.1111/j.1574-6968.2002.tb11020.x"xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/author"Hecker M."xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/author"Ron E.Z."xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/author"Becher D."xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/author"Rosen R."xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/author"Biran D."xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/author"Gur E."xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/date"2002"xsd:gYear
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/name"FEMS Microbiol Lett"xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/pages"9-12"xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/title"Protein aggregation in Escherichia coli: role of proteases."xsd:string
http://purl.uniprot.org/citations/11886743http://purl.uniprot.org/core/volume"207"xsd:string
http://purl.uniprot.org/citations/11886743http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11886743
http://purl.uniprot.org/citations/11886743http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11886743
http://purl.uniprot.org/uniprot/P0A9M0#attribution-3B78231394328DB0162DAEBF37BD048Dhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/11886743