| http://purl.uniprot.org/citations/12130660 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12130660 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12130660 | http://www.w3.org/2000/01/rdf-schema#comment | "Mammalian organogenesis requires the expansion of pluripotent precursor cells before the subsequent determination of specific cell types, but the tissue-specific molecular mechanisms that regulate the initial expansion of primordial cells remain poorly defined. We have genetically established that Six6 homeodomain factor, acting as a strong tissue-specific repressor, regulates early progenitor cell proliferation during mammalian retinogenesis and pituitary development. Six6, in association with Dach corepressors, regulates proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. These data reveal a molecular mechanism by which a tissue-specific transcriptional repressor-corepressor complex can provide an organ-specific strategy for physiological expansion of precursor populations."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1073263"xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1073263"xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Liu F."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Liu F."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Rosenfeld M.G."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Rosenfeld M.G."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Rose D.W."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Rose D.W."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Perissi V."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/author | "Perissi V."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/pages | "1180-1183"xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/pages | "1180-1183"xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/title | "Tissue-specific regulation of retinal and pituitary precursor cell proliferation."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/title | "Tissue-specific regulation of retinal and pituitary precursor cell proliferation."xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/volume | "297"xsd:string |
| http://purl.uniprot.org/citations/12130660 | http://purl.uniprot.org/core/volume | "297"xsd:string |