| http://purl.uniprot.org/citations/12150977 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12150977 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12150977 | http://www.w3.org/2000/01/rdf-schema#comment | "Small ubiquitin-related modifier-1 (SUMO-1) is a protein that is covalently modified to various cellular proteins and protects cells against both anti-Fas and TNF-induced cell death. Previously, we reported that the C-terminus of Daxx interacted with Ubc9, an E2 type SUMO-1 conjugating enzyme, as well as with SUMO-1. In BOSC23 cells expressing FLAG-Daxx together with HA-SUMO-1, 110 and 130kDa Daxx appeared and the 130kDa band bound to both anti-HA and anti-FLAG antibodies. This means that Daxx can be covalently modified by SUMO-1. Substitution of K630 and K631 abrogated the modification of Daxx by SUMO-1, implying that K630 and K631 were essential for sumoylation. Daxx (K630, 631A) and Daxx (K634, 636, 637A) in which the putative C-terminal nuclear localization signals (NLSs) were disrupted appeared in the nucleus, suggesting that the C-terminal NLS was not functional. Daxx (K630, 631A), the sumoylation defective mutant, was able to interact with PML and co-localized with PML in the PML oncogenic domains (PODs). Thus, our data show that sumoylation status of Daxx does not affect its presence in PODs."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0006-291x(02)00699-x"xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0006-291x(02)00699-x"xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/author | "Kim E."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/author | "Kim E."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/author | "Jang M.-S."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/author | "Jang M.-S."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/author | "Ryu S.-W."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/author | "Ryu S.-W."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/pages | "495-500"xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/pages | "495-500"xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/title | "Modification of Daxx by small ubiquitin-related modifier-1."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/title | "Modification of Daxx by small ubiquitin-related modifier-1."xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/volume | "295"xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://purl.uniprot.org/core/volume | "295"xsd:string |
| http://purl.uniprot.org/citations/12150977 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12150977 |
| http://purl.uniprot.org/citations/12150977 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12150977 |
| http://purl.uniprot.org/citations/12150977 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12150977 |
| http://purl.uniprot.org/citations/12150977 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12150977 |