http://purl.uniprot.org/citations/12522250 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12522250 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12522250 | http://www.w3.org/2000/01/rdf-schema#comment | "Lymphatic vessels develop from specialized endothelial cells in preexisting blood vessels, but the molecular signals that regulate this separation are unknown. Here we identify a failure to separate emerging lymphatic vessels from blood vessels in mice lacking the hematopoietic signaling protein SLP-76 or Syk. Blood-lymphatic connections lead to embryonic hemorrhage and arteriovenous shunting. Expression of slp-76 could not be detected in endothelial cells, and blood-filled lymphatics also arose in wild-type mice reconstituted with SLP-76-deficient bone marrow. These studies reveal a hematopoietic signaling pathway required for separation of the two major vascular networks in mammals."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1079477"xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1079477"xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Kahn M.L."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Kahn M.L."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Huang B."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Huang B."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Zhou R."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Zhou R."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Jackson D.G."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Jackson D.G."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Lu M.M."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Lu M.M."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Lowell C.A."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Lowell C.A."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Tybulewicz V."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Tybulewicz V."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Koretzky G.A."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Koretzky G.A."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Mocsai A."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Mocsai A."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Lepore J.J."xsd:string |
http://purl.uniprot.org/citations/12522250 | http://purl.uniprot.org/core/author | "Lepore J.J."xsd:string |