http://purl.uniprot.org/citations/12617819 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12617819 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12617819 | http://www.w3.org/2000/01/rdf-schema#comment | "The Drosophila transmembrane receptor Toll plays a key role in specifying the dorsoventral axis of the embryo. At later stages of development, it controls the immune response of the fly to fungal and Gram-positive bacterial infections. The Drosophila genome has a total of nine Toll-like genes, including the previously characterized Toll (Toll-1) and 18-wheeler (Toll-2). Here we describe the embryonic expression patterns of the seven Toll-like genes Toll-3 through Toll-9. We find that these genes have distinct expression domains and that their expression is dynamically changing throughout embryonic development. This complex and tissue-specific regulation of Toll-like gene expression strongly suggests a role in embryonic development for most Drosophila Tolls. The evolving picture on the Toll family members in Drosophila contrasts with that of mammalian Toll-like receptors, which are predominantly expressed in immune responsive cells where their activation occurs via microbial structural determinants."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1567-133x(02)00020-0"xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1567-133x(02)00020-0"xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/author | "Hoffmann J.A."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/author | "Hoffmann J.A."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/author | "Imler J.L."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/author | "Imler J.L."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/author | "Kambris Z."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/author | "Kambris Z."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/author | "Capovilla M."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/author | "Capovilla M."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/date | "2002"xsd:gYear |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/name | "Gene Expr. Patterns"xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/name | "Gene Expr. Patterns"xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/pages | "311-317"xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/pages | "311-317"xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/title | "Tissue and stage-specific expression of the Tolls in Drosophila embryos."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/title | "Tissue and stage-specific expression of the Tolls in Drosophila embryos."xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/volume | "2"xsd:string |
http://purl.uniprot.org/citations/12617819 | http://purl.uniprot.org/core/volume | "2"xsd:string |
http://purl.uniprot.org/citations/12617819 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12617819 |
http://purl.uniprot.org/citations/12617819 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12617819 |