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http://purl.uniprot.org/citations/12663137http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12663137http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12663137http://www.w3.org/2000/01/rdf-schema#comment"POU homeodomain proteins are important regulators of ubiquitous as well as tissue-specific transcription. Ubiquitously expressed Oct-1 and tissue-specific Oct-2 proteins are members of the POU family and contain very similar DNA-binding POU domains. While Oct-1 is ubiquitous, Oct-2 is predominantly expressed in B cells, in activated T cells and in nervous system. Oct-1 is involved in regulation of some houskeeping genes-histone H2B, snRNAs as well as in tissue-specific regulation of immunoglobuline gene transcription and of some other genes. Here we report that novel alternatively spliced product of the human Oct-1 gene encode Oct-1L isoform with tissue-specific expression pattern, similar to Oct-2. Oct-1L differ from ubiquitously expressed Oct-1A in 5'-terminal exon (exon 1L). Analysis of nucleotide sequences from Human Genome Data Bank has located exon 1L about 108 kbp downstream ubiquitously expressed exon 1U. Amino terminus of Oct-1L show extensive similarity to amino terminus of Oct-2. We suppose, that Oct-1L may has a specific role in gene expression in lymphoid tissues and brain."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.org/dc/terms/identifier"doi:10.1016/s0165-2478(02)00179-7"xsd:string
http://purl.uniprot.org/citations/12663137http://purl.org/dc/terms/identifier"doi:10.1016/s0165-2478(02)00179-7"xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/author"Krivega I.V."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/author"Krivega I.V."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/author"Luchina N.N."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/author"Luchina N.N."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/author"Pankratova E.V."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/author"Pankratova E.V."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/name"Immunol. Lett."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/name"Immunol. Lett."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/pages"237-241"xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/pages"237-241"xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/title"Human Oct-1L isoform has tissue-specific expression pattern similar to Oct-2."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/title"Human Oct-1L isoform has tissue-specific expression pattern similar to Oct-2."xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/volume"85"xsd:string
http://purl.uniprot.org/citations/12663137http://purl.uniprot.org/core/volume"85"xsd:string
http://purl.uniprot.org/citations/12663137http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12663137
http://purl.uniprot.org/citations/12663137http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12663137
http://purl.uniprot.org/citations/12663137http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12663137
http://purl.uniprot.org/citations/12663137http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/12663137