| http://purl.uniprot.org/citations/12826663 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12826663 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/12826663 | http://www.w3.org/2000/01/rdf-schema#comment | "Nectins are Ca2+-independent immunoglobulin-like cell-cell adhesion molecules that play roles in organization of a variety of cell-cell junctions in cooperation with or independently of cadherins. Four nectins have been identified. Five nectin-like molecules, which have domain structures similar to those of nectins, have been identified, and we characterized here nectin-like molecule-2 (Necl-2)/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1. Necl-2 showed Ca2+-independent homophilic cell-cell adhesion activity. It furthermore showed Ca2+-independent heterophilic cell-cell adhesion activity with Necl-1/TSLL1/SynCAM3 and nectin-3. Necl-2 was widely expressed in rat tissues examined. Necl-2 localized at the basolateral plasma membrane in epithelial cells of the mouse gall bladder, but not at specialized cell-cell junctions, such as tight junctions, adherens junctions, and desmosomes. Nectins bind afadin, whereas Necl-2 did not bind afadin but bound Pals2, a membrane-associated guanylate kinase family member known to bind Lin-7, implicated in the proper localization of the Let-23 protein in Caenorhabditis elegans, the homologue of mammalian epidermal growth factor receptor. These results indicate the unique localization of Necl-2 and its possible involvement in localization of a transmembrane protein(s) through Pals2."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m305387200"xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m305387200"xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Imai T."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Imai T."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Satoh K."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Satoh K."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Takai Y."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Takai Y."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Takeuchi M."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Takeuchi M."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Itoh S."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Itoh S."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Morimoto K."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Morimoto K."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Ikeda W."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Ikeda W."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Monden M."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Monden M."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Kakunaga S."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Kakunaga S."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Shingai T."xsd:string |
| http://purl.uniprot.org/citations/12826663 | http://purl.uniprot.org/core/author | "Shingai T."xsd:string |