http://purl.uniprot.org/citations/12860405 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12860405 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/12860405 | http://www.w3.org/2000/01/rdf-schema#comment | "Interleukin-1 (IL-1) receptor-associated kinases (IRAKs) are central components of Toll/IL-1 receptor (TIR) signaling pathways. In an attempt to discover novel signal transducers in TIR signaling, we identified human Pellino2 as an interaction partner of IRAK4. Pellino2 interacts with kinase-active as well as kinase-inactive IRAK1 and IRAK4. Furthermore, Pellino2 is one of the first substrates identified for IRAK1 and IRAK4. Functional studies using overexpression or RNAi knock-down of Pellino2 suggest a role of Pellino2 as a scaffolding protein similar to Pellino1. However, unlike Pellino1, Pellino2 does not seem to activate a specific transcription factor, but links TIR signaling to basic cellular processes."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(03)00697-5"xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(03)00697-5"xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/author | "Strelow A."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/author | "Strelow A."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/author | "Wesche H."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/author | "Wesche H."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/author | "Kollewe C."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/author | "Kollewe C."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/pages | "157-161"xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/pages | "157-161"xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/title | "Characterization of Pellino2, a substrate of IRAK1 and IRAK4."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/title | "Characterization of Pellino2, a substrate of IRAK1 and IRAK4."xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/volume | "547"xsd:string |
http://purl.uniprot.org/citations/12860405 | http://purl.uniprot.org/core/volume | "547"xsd:string |
http://purl.uniprot.org/citations/12860405 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12860405 |
http://purl.uniprot.org/citations/12860405 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/12860405 |
http://purl.uniprot.org/citations/12860405 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12860405 |
http://purl.uniprot.org/citations/12860405 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/12860405 |