RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/12965222http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12965222http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/12965222http://www.w3.org/2000/01/rdf-schema#comment"The liver endoplasmic reticulum glucose-6-phosphatase catalytic subunit (G6PC1) catalyses glucose 6-phosphate hydrolysis during gluconeogenesis and glycogenolysis. The highest glucose-6-phosphatase activities are found in the liver and the kidney; there have been many reports of glucose 6-phosphate hydrolysis in other tissues. We cloned a new G6Pase isoform (G6PC3) from human brain encoded by a six-exon gene (chromosome 17q21). G6PC3 protein was able to hydrolyse glucose 6-phosphate in transfected Chinese hamster ovary cells. The optimal pH for glucose 6-phosphate hydrolysis was lower and the K(m) higher relative to G6PC1. G6PC3 preferentially hydrolyzed other substrates including pNPP and 2-deoxy-glucose-6-phosphate compared to the liver enzyme."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(03)00903-7"xsd:string
http://purl.uniprot.org/citations/12965222http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(03)00903-7"xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/author"Stafford K."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/author"Stafford K."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/author"Clottes E."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/author"Clottes E."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/author"Burchell A."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/author"Burchell A."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/author"Guionie O."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/author"Guionie O."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/pages"159-164"xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/pages"159-164"xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/title"Identification and characterisation of a new human glucose-6-phosphatase isoform."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/title"Identification and characterisation of a new human glucose-6-phosphatase isoform."xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/volume"551"xsd:string
http://purl.uniprot.org/citations/12965222http://purl.uniprot.org/core/volume"551"xsd:string
http://purl.uniprot.org/citations/12965222http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12965222
http://purl.uniprot.org/citations/12965222http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/12965222