| http://purl.uniprot.org/citations/1346576 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1346576 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1346576 | http://www.w3.org/2000/01/rdf-schema#comment | "The CD11b/CD18 heterodimeric surface antigen is expressed exclusively on human monocytes, macrophages, granulocytes, and natural killer cells. During differentiation of myeloid cell lines, CD11b steady state messenger RNA levels increase significantly; we show here that CD11b transcription rates increase commensurately. A 1.7-kb fragment of CD11b 5' flanking sequence directs expression of a reporter gene specifically in myeloid cell lines. Deletion analysis localizes elements directing high levels of tissue-specific reporter gene expression to the 412 bp proximal to the transcriptional start site. This sequence contains two consensus binding sites for Sp1, a GATA motif, and a purine-rich sequence that presents potential binding sites for members of the ets family of genes. Analysis of this promoter should result in the isolation of myeloid-specific transcription factors and the development of methods to direct the myeloid-specific expression of heterologous genes."xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/author | "Tenen D.G."xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/author | "Tenen D.G."xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/author | "Pahl H.L."xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/author | "Pahl H.L."xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/author | "Rosmarin A.G."xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/author | "Rosmarin A.G."xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/name | "Blood"xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/name | "Blood"xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/pages | "865-870"xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/pages | "865-870"xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/title | "Characterization of the myeloid-specific CD11b promoter."xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/title | "Characterization of the myeloid-specific CD11b promoter."xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/volume | "79"xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://purl.uniprot.org/core/volume | "79"xsd:string |
| http://purl.uniprot.org/citations/1346576 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1346576 |
| http://purl.uniprot.org/citations/1346576 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1346576 |
| http://purl.uniprot.org/citations/1346576 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1346576 |
| http://purl.uniprot.org/citations/1346576 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1346576 |
| http://purl.uniprot.org/uniprot/P11215 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1346576 |
| http://purl.uniprot.org/uniprot/#_kb.P11215_up.isolatedFrom_tissue.79 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1346576 |