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http://purl.uniprot.org/citations/14552798http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14552798http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/14552798http://www.w3.org/2000/01/rdf-schema#comment"The analysis of the X-ray structures of two xanthine inhibitors bound to PEPCK and a comparison to the X-ray structure of GTP bound to PEPCK are reported. The SAR at N-1, N-7 and developing SAR at C-8 are consistent with information gained from the X-ray structures of compounds 1 and 2 bound to PEPCK. Representative N-3 modifications of compound 2 that led to the discovery of 3-cyclopropylmethyl and its carboxy analogue as optimal N-3 groups are presented."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.org/dc/terms/identifier"doi:10.1016/s0960-894x(03)00723-6"xsd:string
http://purl.uniprot.org/citations/14552798http://purl.org/dc/terms/identifier"doi:10.1016/s0960-894x(03)00723-6"xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Wang P."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Wang P."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Dunten P."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Dunten P."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Foley L.H."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Foley L.H."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Gubler M.L."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Gubler M.L."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Ramsey G."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Ramsey G."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Wertheimer S.J."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/author"Wertheimer S.J."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/date"2003"xsd:gYear
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/name"Bioorg. Med. Chem. Lett."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/name"Bioorg. Med. Chem. Lett."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/pages"3871-3874"xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/pages"3871-3874"xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/title"X-ray structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-dibenzylxanthines."xsd:string
http://purl.uniprot.org/citations/14552798http://purl.uniprot.org/core/title"X-ray structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-dibenzylxanthines."xsd:string