| http://purl.uniprot.org/citations/14595002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14595002 | http://www.w3.org/2000/01/rdf-schema#comment | "Serum amyloid A (SAA) circulates bound to HDL3 during the acute-phase response (APR), and recent evidence suggests that elevated levels of SAA may be a risk factor for cardiovascular disease. In this study, SAA-HDL was produced in vivo during the APR and without the APR by injection of an adenoviral vector expressing human SAA-1. SAA-HDL was also produced in vitro by incubating mouse HDL with recombinant mouse SAA and by SAA-expressing cultured hepatoma cells. Whether produced in vivo or in vitro, SAA-HDL floated at a density corresponding to that of human HDL3 (d 1.12 g/ml) separate from other apolipoproteins, including apolipoprotein A-I (apoA-I; d 1.10 g/ml) when either apoA-I or apolipoprotein E (apoE) was present. In the absence of both apoA-I and apoE, SAA was found in VLDL and LDL, with low levels in the HDL and the lipid-poor fractions suggesting that other HDL apolipoproteins are incapable of facilitating the formation of SAA-HDL. We conclude that SAA does not exist in plasma as a lipid-free protein. In the presence of HDL-associated apoA-I or apoE, SAA circulates as SAA-HDL with a density corresponding to that of human HDL3. In the absence of both apoA-I and apoE, SAA-HDL is not formed and SAA associates with any available lipoprotein."xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.org/dc/terms/identifier | "doi:10.1194/jlr.m300414-jlr200"xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/author | "Feng N."xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/author | "Webb N.R."xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/author | "Reardon C.A."xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/author | "Getz G.S."xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/author | "de Beer F.C."xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/author | "Cabana V.G."xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/author | "Lukens J."xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/date | "2004"xsd:gYear |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/name | "J Lipid Res"xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/pages | "317-325"xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/title | "Influence of apoA-I and apoE on the formation of serum amyloid A-containing lipoproteins in vivo and in vitro."xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://purl.uniprot.org/core/volume | "45"xsd:string |
| http://purl.uniprot.org/citations/14595002 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/14595002 |
| http://purl.uniprot.org/citations/14595002 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/14595002 |
| http://purl.uniprot.org/uniprot/P08226#attribution-8BAA450574F0727D584608415280E95B | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/14595002 |
| http://purl.uniprot.org/uniprot/Q00623#attribution-8C075B85B1062C96B6A739B672B31937 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/14595002 |
| http://purl.uniprot.org/uniprot/P21784#attribution-7C87BD6CBD1070D413C381E0028FB267 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/14595002 |
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| http://purl.uniprot.org/uniprot/#_A0A1B0GX15-mappedCitation-14595002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14595002 |
| http://purl.uniprot.org/uniprot/#_B7ZMX3-mappedCitation-14595002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14595002 |
| http://purl.uniprot.org/uniprot/#_G3UWN5-mappedCitation-14595002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14595002 |
| http://purl.uniprot.org/uniprot/#_G3UWW2-mappedCitation-14595002 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/14595002 |