| http://purl.uniprot.org/citations/14636573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14636573 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/14636573 | http://www.w3.org/2000/01/rdf-schema#comment | "Transcriptional coactivators showing physical and functional interactions with PPARgamma include the protein acetyl transferase p300, the TRAP/Mediator complex that interacts with the general transcription machinery, and the highly regulated PGC-1alpha. We show that PGC-1alpha directly interacts with TRAP/Mediator, through the PPARgamma-interacting subunit TRAP220, and stimulates TRAP/Mediator-dependent function on DNA templates. Further, while ineffective by itself, PGC-1alpha stimulates p300-dependent histone acetylation and transcription on chromatin templates in response to PPARgamma. These functions are mediated by largely independent PPARgamma, p300, and TRAP220 interaction domains in PGC-1alpha, whereas p300 and TRAP220 show ligand-dependent interactions with a common region of PPARgamma. Apart from showing PGC-1alpha functions both in chromatin remodeling and in preinitiation complex formation or function (transcription), these results suggest a key role for PGC-1alpha, through concerted but dynamic interactions, in coordinating these steps."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(03)00391-5"xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(03)00391-5"xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Yamamura S."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Yamamura S."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Malik S."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Malik S."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Spiegelman B.M."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Spiegelman B.M."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Roeder R.G."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Roeder R.G."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Wallberg A.E."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/author | "Wallberg A.E."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/date | "2003"xsd:gYear |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/pages | "1137-1149"xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/pages | "1137-1149"xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/title | "Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/title | "Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha."xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/volume | "12"xsd:string |
| http://purl.uniprot.org/citations/14636573 | http://purl.uniprot.org/core/volume | "12"xsd:string |